We thank Prof Azim Surani for kindly giving us the mEpiSC cell line, and thank Tao Chen, Dr Yongfan Men, Zhilong Yu, Zitian Chen, Dr Liang Zhao, Haiwei Qiu, Lu Yang and Dr Yun Zhang for discussion and experimental help. This work was supported by the Ministry of Science and Technology of China (2011CB809106, 2012CB966704) and the National Natural Science Foundation of China (21222501, 21327808, 31271543, 91313302). AMS was supported by the Whitaker International Biomedical Engineering Fellowship.
Dear Editor, Epigenetic regulation is crucial to the establishment and maintenance of the identity of a cell. Recent stud- ies suggest that transcription is implemented amongst a mixture of various histone modificatio...
supported by the National Natural Science Foundation of China (20733001, 20890020, 90913011, 20905004);the Ministry of Science and Technology of China (2011CB809106);the Ministry of Education of China;the Fok Ying Tung Education Foundation
We developed an integrated microfluidic chip for long-term culture of isolated single cells. This polydimethylsiloxane (PDMS) based device could accurately seed each single cell into different culture chambers, and is...