This project was supported by the grants from National Natural Science Foundation of China(81173120,81302834);Major Program of National Natural Science Foundation of China(2012ZX09506001-004).
RNA interference(RNAi)is useful for selective gene silencing.Cytochrome P4503A4(CYP3A4),which metabolizes approximately 50% of drugs in clinical use,plays an important role in drug metabolism.In this study,we aimed to...