云南高校图书馆联盟文献共享服务平台- 国家自然科学基金(81272075)

国家自然科学基金(81272075): 作品数：10被引量：14H指数：2; 导出分析报告; 相关作者：陆远强姜久昆张琴徐佳吴建民更多>>; 相关机构：浙江大学医学院附属第一医院建德市第一人民医院更多>>; 相关期刊：《World Journal of Emergency Medicine》《中华危重症医学杂志（电子版）》《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》更多>>; 相关主题：失血性休克AFTER髓系抑制性细胞HEMORRHAGICRESUSCITATION更多>>; 相关领域：医药卫生更多>>

Analysis of imaging characteristics of blunt traumatic aortic dissection: an 8-year experience被引量：1: 《World Journal of Emergency Medicine》2022年第5期361-366,共6页Li Li Li-ying Lin Yuan-qiang Lu; This study was supported by the National Natural Science Foundation of China(81272075 and 81801572);the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine(2017-XK-A36).; BACKGROUND:Traumatic aortic dissection(TAD)has a low incidence but extremely high mortality.It always presents atypical clinical manifestations that are easily missed or misdiagnosed.This study mainly aims to describe...; 关键词：Blunt trauma Traumatic aortic dissection Imaging characteristic DIAGNOSIS Delayed thoracic endovascular aortic repair

增龄性免疫衰老与免疫抑制网络被引量：1: 《中华危重症医学杂志（电子版）》2021年第1期3-9,共7页徐佳陆远强; 国家自然科学基金项目(81801572、81272075);“十三五”浙江省中医药(中西医结合)重点学科项目(2017-XKA36)。; 随着社会老龄化的加重,增龄性免疫衰老研究已经成为国际上新的热点。免疫衰老是导致老年人感染、肿瘤和自身免疫性疾病发病率和病死率居高不下的重要因素,与疫苗接种效率下降及2型糖尿病、动脉粥样硬化、骨质疏松、关节炎等衰老相关疾...; 关键词：免疫衰老炎性衰老免疫抑制网络髓源抑制细胞

Role of routine check-up in the prognosis of patients with pancreatic cancer:A puzzling phenomenon: 《Hepatobiliary & Pancreatic Diseases International》2021年第1期67-73,共7页Cong-Ying Song Yan Shen Yuan-Qiang Lu; the National Natural Science Foundation of China(81272075 and 81801572);the Medical and Health Science Foundation of Zhejiang Province(2019327552);the Foundation of Key Research Project of Zhejiang Province for Traditional Chinese Medicine(2019ZZ014);the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine(2017-XKA36).; Background:The high coverage of annual routine health check-up in China is a unique phenomenon throughout the world.However,its clinical value is controversial.In this cohort study,we chose pancreatic cancer as a dise...; 关键词：Pancreatic cancer Routine check-up Early detection Survival rate

Comparative transcriptomic analysis of vascular endothelial cells after hypoxia/re-oxygenation induction based on microarray technology被引量：1: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2020年第4期291-304,共14页Jia XU Jiu-kun JIANG Xiao-lin LI Xiao-peng YU Ying-ge XU Yuan-qiang LU; Project supported by the National Natural Science Foundation of China(Nos.81801572 and 81272075);the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine(No.2017-XKA36);the Foundation of Key Research Project of Zhejiang Province for Traditional Chinese Medicine(No.2019ZZ014);the Medical and Health Science Foundation of Zhejiang Province(No.2019327552);the Key Research and Development Program of Zhejiang Province(No.2019C03076);the General Research Program of Zhejiang Provincial Department of Medical and Health(No.2013KYA066);the Opening Foundation of State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases(Nos.2018KF02 and 2019KF06);the Program of Education Department of Zhejiang Province(No.Y201738150),China。; Objective: To provide comprehensive data to understand mechanisms of vascular endothelial cell(VEC) response to hypoxia/re-oxygenation. Methods: Human umbilical vein endothelial cells(HUVECs) were employed to construc...; 关键词：Human umbilical vein endothelial cells(HUVECs) HYPOXIA Re-oxygenation MICROARRAY Pleckstrin homology-like domain family A member 1(PHLDA1) Long non-coding RNA(lncRNA)

Immune recovery after fluid resuscitation in rats with severe hemorrhagic shock被引量：3: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第5期402-409,共8页Feng YAO Yuan-qiang LU Jiu-kun JIANG Lin-hui GU Han-zhou MOU; supported by the National Natural Science Foundation of China(No.81272075); Objective： To investigate the effects of resuscitation with normal saline（NS）, hypertonic saline（HTS）, and hydroxyethyl starch（HES） on regulatory T cells（Tregs）, helper T 1（Th1）/Th2 and cytotoxic T 1（Tc1）...; 关键词：Regulatory T cells Helper T cells Cytotoxic T cells Hemorrhagic shock

Distribution and differentiation of myeloid-derived suppressor cells after fluid resuscitation in mice with hemorrhagic shock: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第1期48-58,共11页Jiu-kun JIANG Wen FANG Liang-jie HONG Yuan-qiang LU; Project supported by the National Natural Science Foundation of China(No.81272075); Objective： To investigate the distribution and differentiation of myeloid-derived suppressor cells （MDSCs） in hemorrhagic shock mice, which are resuscitated with normal saline （NS）, hypertonic saline （HTS）, and...; 关键词：Hemorrhagic shock Hydroxyethyl starch Hypertonic saline Myeloid-derived suppressor cells Normal saline

失血性休克大鼠肺细胞HO-1 mRNA表达和凋亡的相关性研究: 《中华危重症医学杂志（电子版）》2014年第4期5-8,共4页吴建民胡世宏张琴姜久昆; 国家自然科学基金项目(编号:81272075);浙江省自然科学基金项目(Y2100430); 目的检测和分析失血性休克大鼠肺细胞HO-1 mRNA表达及凋亡的发生情况,从而探讨其临床意义。方法本研究将14只SD大鼠制成重度失血性休克模型,使用SYBR Green I实时荧光定量逆转录-聚合酶链反应技术和流式细胞仪FITC-Annexin V/PI荧光染色...; 关键词：失血性休克细胞凋亡血红素氧合酶-1 基因表达

重视失血性休克后髓系抑制性细胞的免疫机制研究被引量：2: 《中华危重症医学杂志（电子版）》2013年第5期2-4,共3页陆远强姜久昆; 国家自然科学基金资助项目(81272075); 失血性休克是临床上的常见急危重症，积极的液体复苏和针对原发病的治疗是失血性休克早期抢救的关键环节。既往研究表明，在失血性休克的初期，机体的免疫炎症反应系统即被激活，经过适当的液体复苏和药物治疗后，机体的微循环障碍往往...; 关键词：失血性休克免疫机制抑制性免疫炎症反应细胞髓系病理生理过程病理生理基础

Hypertonic saline resuscitation contributes to early accumulation of circulating myeloid-derived suppressor cells in a rat model of hemorrhagic shock被引量：8: 《Chinese Medical Journal》2013年第7期1317-1322,共6页LU Yuan-qiang GU Lin-hui ZHANG Qin JIANG Jiu-kun MOU Han-zhou; Science Foundation of China （No. 81272075）, Zhejiang Provincial Natural Science Foundation of China （No. Y2100430）, and the Zhejiang Provincial Education and Research Foundation of China （No. Y201019154）.; Background Hemorrhagic shock is usually associated with complicated immune and inflammatory responses, which are sometimes crucial for the prognosis. As regulators of the immune and inflammatory system; proliferation,...; 关键词：shock hemorrhagic RESUSCITATION saline solution hypertonic myeloid-derived suppressor cells

失血性休克大鼠中髓系抑制性细胞变化规律的初步研究被引量：1: 《中华危重症医学杂志（电子版）》2012年第6期5-9,共5页郑元回张琴姜久昆陆远强; 温州市科技计划项目(Y20100355);浙江省教育厅科研项目(编号:Y201019154);浙江省自然科学基金项目(Y2100430);国家自然科学基金项目(编号:81272075); 目的探讨失血性休克大鼠早期外周血、脾脏及骨髓中髓系抑制性细胞(MDSCs)的初步变化规律。方法将14只SD大鼠随机分为两组:对照组和失血性休克组,每组7只。失血性休克组大鼠建立重度失血性休克模型,模拟急救流程,即分为失血期、早期复苏...; 关键词：失血性休克髓系抑制性细胞流式细胞术

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