Supported by the National Natural Science Foundation of China(No.81273870);Chongqing Municipal Health and Family Planning Commission and Chongqing Municipal Science and Technology Commission Jointly Funded Key Research Projects in Traditional Chinese Medicine(No.ZY201801007);Beibei District Chongqing Basic Research and Frontier Exploration Project(No.2019-6)。
OBJECTIVE:To investigate the effect of manipulation treatment on knee osteoarthritis rats and the effect on Rho-associated protein kinase(ROCK)/LIM-kinase1(LIMK1)/Cofilin signaling pathway.METHOD:Fifty Specific pathog...