国家自然科学基金(s81102483)

作品数:1被引量:3H指数:1
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相关期刊:《Chinese Journal of Natural Medicines》更多>>
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Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation被引量:3
《Chinese Journal of Natural Medicines》2014年第3期186-193,共8页ZHANG Xuan HUANG Sheng-Zhuo GU Wan-Gang YANG Liu-Meng CHEN Huan ZHENG Chang-Bo ZHAO You-Xing WAN David Chi-Cheong ZHENG Yong-Tang 
supported,in part,by grants from the National Natural Science Foundation of China(Nos.81102483,81001462);the 973 Program(No.2009CB522306);the Key Scientific and Technological Program of China(Nos.2009-ZX09501-029,2012ZX10001-006,2012ZX10001-007,2012ZX-09103-101-022),and Yunnan(No.2010GA001)
AIM: To evaluate the anti-HIV activity and mechanism of action of wikstroelide M, a daphnane diterpene from Daphne acutiloba Rehder (Thymelaeaceae). METHOD: The anti-HIV activities of wikstroelide M against differ...
关键词:Wikstroelide M Daphnane diterpene Daphne acutiloba Rehder HIV Reverse trascriptase INTEGRASE Nucleartranslocation Lens epithelium-derived growth factor (LEDGF/p75) Molecular docking 
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