国家自然科学基金(ZJY0505)

作品数:3被引量:38H指数:3
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相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》更多>>
相关主题:INSULINCINODUDIABETESEXTRACELLULAR_MATRIX更多>>
相关领域:医药卫生更多>>
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Notch signaling: a novel regulating differentiation mechanism of human umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells in vitro被引量:7
《Chinese Medical Journal》2010年第5期606-614,共9页HU Yan-hua WU De-quan GAO Feng LI Guo-dong ZHANG Xin-chen 
This work was supported by the grants from the Natural Science Foundation of Heilongjiang Province (No. ZJY0505) and the Innovation of Foundation of Backbone Teachers of Heilongjiang Provincial University (No. 1054G026).
Background Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) could be induced to differentiate into insulin producing cells (IPCs) in vitro, which have good application potential in the cell rep...
关键词:Notch signaling mesenchymal stem cells DIFFERENTIATION insulin producing cells DIABETES 
A secretory function of human insulin-producing cells in vivo被引量:3
《Hepatobiliary & Pancreatic Diseases International》2009年第3期255-260,共6页Hu, Yan-Hua Wu, De-Quan Gao, Feng Li, Guo-Dong Yao, Lei Zhang, Xin-Chen 
supported by grants from the Natural Science Foundation of Heilongjiang Province(No.ZJY0505);the Innovation of Foundation of Outstanding Teachers of Heilongjiang Provincial University(No.1054G026)
BACKGROUND: Mesenchymal stem cells derived from human umbilical cord blood (UCB-MSCs) have good research and application prospects in the treatment of diabetes. We once induced UCB-MSCs to differentiate into insulin-p...
关键词:human umbilical cord blood mesenchymal stem cells insulin-producing cells DIABETES cell transplantation 
Extracellular matrix gel is necessary for in vitro cultivation of insulin producing cells from human umbilical cord blood derived mesenchymal stem cells被引量:31
《Chinese Medical Journal》2008年第9期811-818,共8页GAO Feng WU De-quan HU Yan-hua JIN Guang-xin 
This work was supported by the Natural Science Foundation of Heilongjiang Province (No. ZJY0505).
Background Pancreatic islet cell transplantation is an effective approach to treat type 1 diabetes. However, this therapy is not widely used because of the severe shortage of transplantable donor islets. This study in...
关键词:umbilical cord blood mesenchymal stem cells induction insulin producing cells extracellular matrix 
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