This work was supported by the grants from the National Natural Science Foundation of China (Nos. 81460173, 81260061 and 81260297), the Yunnan Applied Basic Research Projects-Joint Special Project (Nos. 2012FB013 and 2013FB101), and the Key Project of Yunnan Provincial Education Commission (No. 2014Z128).
Oxidative stress, inflammatory response, and mitogen-activated protein kinases (MAPKs) cascade are significant pathogenic factors of osteoporosis. It has been reported that elevated homocysteine (Hcy) may activate...