国家自然科学基金(31129003)

作品数：2被引量：6H指数：2
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Activation of extrasynaptic GABA_A receptors inhibits cyclothiazideinduced epileptiform activity in hippocampal CA1 neurons被引量：3
《Neuroscience Bulletin》2014年第5期866-876,共11页Li Wan Xu Liu Zheng Wu Wanting Ren Shuzhen Kong Raya Abou Dargham Longzhen Cheng Yun Wang 
supported by grants from the National Natural Science Foundation of China(31129003,81100815,81171224, 81401082,and 81301108);the Science and Technology Commission of Shanghai Municipality,China(13DJ1400302, 13ZR1406500,and 11ZR1401700)
Extrasynaptic GABAA receptors （GABAARs）-mediated tonic inhibition is reported to involve in the patho- genesis of epilepsy. In this study, we used cyclo- thiazide （CTZ）-induced in vitro brain slice seizure model t...
关键词：GABAARS tonic inhibition EPILEPSY population spike CYCLOTHIAZIDE hippocampal CA1 neurons 
BDNF–TrkB signaling pathway is involved in pentylenetetrazoleevoked progression of epileptiform activity in hippocampal neurons in anesthetized rats被引量：3
《Neuroscience Bulletin》2013年第5期565-575,共11页Xu Liu Jia Liu Juan Liu Xiao-Ling Liu Ling-Yan Jin Wei Fan Jin Ding Li-Chao Peng Yun Wang Xin Wang 
supported by grants from the National Natural Science Foundation of China (31129003, 81171224, and 31271188);Shanghai Municipal Science and Technology Commission, China (10JC1402800);Shanghai Municipal Health Bureau, China (20114218)
Pentylenetetrazole（PTZ）is a widely-used convulsant used in studies of epilepsy;its subcutaneous injection generates an animal model with stable seizures.Here,we compared the ability of PTZ via the intravenous and su...
关键词：epilepsy pentamethylenetetrazole hippocampus BDNF TrkB 
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