国家自然科学基金(30670937)

作品数：2被引量：14H指数：2
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Type I natural killer T cells： naturally born for fighting被引量：9
《Acta Pharmacologica Sinica》2010年第9期1123-1132,共10页Jin-quan TAN Wei XIAO Lan WANG Yu-ling HE 
This work was supported by the grants from the National Natural Science Foundation of China （30730054, 30572119, 30670937, 30971279, 30901363）, the Hi-tech Research and Development Program of China from Ministry of Science and Technology （2007AA02Z120）, the Ministry of Education （20060486008, 20090141120011）, Provincial Department of Science and Tech- nology of Hubei （2007ABC010）, Provincial Department of Health of Hubei （JX4B14）, Innovation Program of Wuhan Uni- versity for Young Scholars （WU3082007）, National Innovation Experiment Program for College Students （WU2007061）, China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China （Chang Jiang Scholar TJ）.
Type I natural killer T cells （NKT cells）, a subset of CDld-restricted T cells with invariant Vαβ TCR, are characterized by prompt production of large amounts of Thl and/or Th2 cytokines upon primary stimulation t...
关键词：NKT cells tumor immunity cell development and homeostasis Th1/Th2 cytokines 
EBV-Induced Human CD8^＋ NKT Cells Synergise CD4^＋ NKT Cells Suppressing EBV-Associated Tumours upon Induction of Thl-Bias被引量：5
《Cellular & Molecular Immunology》2009年第5期367-379,共13页Wei Xiao Li Li Rui Zhou Ruijing Xiao Yujuan Wang Xiang Ji Mengjun Wu Lan Wang Wei Huang Xiaoling Zheng Xinti Tan Lang Chen Tao Xiong Jie Xiong Youxin Jin Jinquan Tan Yuling He 
Acknowledgements This work was supported by the grants from the National Natural Science Foundation of China （30730054, 30572119, 30670937, 30971279, 30901363）, the Hi-tech Research and Development Program of China from Ministry of Science and Technology （2007AA02Z120）, the Ministry of Education （20060486008）, National Innovation Experiment Program for College Students （WU2007061）, Provincial Departrnent of Science and Technology of Hubei （2007ABC010）, China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China （Chang Jiang Scholar T.J.）.
CD8^＋ natural killer T （NKT） cells from EBV-associated tumour patients are quantitatively and functionally impaired. EBV-induced CD8^＋ NKT cells drive syngeneic T cells into a Thl-bias response to suppress EBV-ass...
关键词：CD8^＋ NKT cells EBV human-thymus-SCID chimaeras IFN-γ 
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