国家自然科学基金(21090352)

作品数：3被引量：3H指数：1
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相关期刊：《Chinese Journal of Chemistry》《Chinese Journal of Polymer Science》更多>>
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Effects of Chirality on Gene Delivery Efficiency of Polylysine被引量：3
《Chinese Journal of Polymer Science》2016年第1期94-103,共10页Bin-wei Zhao Zhuxian Zhou 申有青 
financially supported by the National Basic Research Program(No.2014CB931900);the National Natural Science Foundation of China(No.21090352)
Chirality is a key factor in the biological activity of many biomolecules. Poly（L-lysine）（PLL）, a polypeptide synthesized from L-lysine, is one of the mostly used cationic polymers for gene delivery. The effect of...
关键词：Gene delivery Gene transfection Chiral effects Polylysine 
Synthesis and Properties of a Biodegradable Dendritic Magnetic Resonance Imaging Contrast Agent
《Chinese Journal of Chemistry》2014年第1期91-96,共6页Tingting Li Yue Qian Mingzhou Ye Jianbin Tang Hongjie Hu Youqing Shen 
This work was financially supported by the National Natural Science Foundation of China (Nos.20904046,21174128,and 21090352) and the Qianjiang Talent Program of Zhejiang Province of China (No.2010R10050).
Novel biodegradable dendritic contrast agents (DCAs) based on polyester dendrimers were synthesized and characterized.The DCAs were stable at acidic pH,but hydrolyzed rapidly at physiological pH,which rendered the DCA...
关键词：DENDRIMER magnetic resonance imaging BIODEGRADABLE tumor imaging 
WHAT CAN WE LEARN FROM VIRUS IN DESIGNING NONVIRAL GENE VECTORS
《Chinese Journal of Polymer Science》2011年第3期274-287,共14页申有青 
supported by the Distinguished Young Scholars(No.50888001);National Natural Science Foundation of China(No.21090352);National Basic Research Program(973 Program,2009CB526403);Program for Changjiang Scholars and Innovative Research Team in University of China and Fundamental Research Funds for Central Universities(No.2010QNA4022)
Gene therapy has emerged as a potential new approach to treat genetic disorders by delivering therapeutic genes to target diseased tissues. However, its clinical use has been impeded by gene delivery systems. The vira...
关键词：Gene therapy Gene delivery VIRUS Nonviral vectors Cationic polymers. 
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