国家重点基础研究发展计划(2010CB934001)

作品数:2被引量:5H指数:2
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Surface-modulated and thermoresponsive polyphosphoester nanoparticles for enhanced intracellular drug delivery被引量:2
《Science China Chemistry》2014年第4期579-585,共7页LI Yang WANG Feng SUN TianMeng DU JinZhi YANG XianZhu WANG Jun 
supported by the Ministry of Science and Technology of China(2010CB934001);the National Natural Science Foundation of China(51125012,51203145)
The chemical structure of end groups influenced the phase transition temperature of thermoresponsive polymers. We demonstrated a strategy for the preparation of the pH/thermo-responsive polymeric nanoparticles via sub...
关键词:THERMORESPONSIVE drug release POLYPHOSPHOESTER drug resistance 
Phosphoester modified poly(ethylenimine) as efficient and low cytotoxic genevectors被引量:3
《Science China Chemistry》2011年第2期351-358,共8页DU JinZhi TANG LingYan YUAN YouYong WANG Jun 
supported by the National Basic Research Program of China (973 Program,2010CB934001)
Cyclic phosphoester monomer ethyl ethylene phosphate (EEP) modified poly(ethylenimine) (PEI),denoted as PEI-EEP,was developed for gene delivery.Three PEI-EEP polymers were synthesized and their structures were charact...
关键词:gene delivery PEI phosphoester gene vector 
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