POLYPHOSPHOESTER

作品数:10被引量:23H指数:3
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相关领域:医药卫生理学更多>>
相关期刊:《Chemical Research in Chinese Universities》《Journal of Wuhan University of Technology(Materials Science)》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金国家高技术研究发展计划更多>>
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Monoclonal Antibody-conjugated Polyphosphoester-hyd-DOX Prodrug Nanoparticles for Targeted Chemotherapy of Liver Cancer Cells被引量:1
《Chinese Journal of Polymer Science》2021年第11期1392-1402,共11页Ya-Kui Huang Hong-Rui Tian Ming-Zu Zhang Jin-Lin He Jian Liu Pei-Hong Ni 
financial supports from the National Natural Science Foundation of China(Nos.21975169 and 21374066);the Natural Science Foundation of Jiangsu Province(No.BK20171212);Funded by the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions。
In order to overcome the limitation of traditional active nano-therapeutic drugs on tumor targeting efficiency which cannot reach the receptor/target in sufficient amount in the body,in this work,we developed a monocl...
关键词:Monoclonal antibody Polymeric prodrug POLYPHOSPHOESTER Drug delivery Targeted therapy 
Polyphosphoester-modified Cellulose Nanocrystals for Stabilizing Pickering Emulsion Polymerization of Styrene被引量:1
《Chinese Journal of Polymer Science》2020年第9期921-931,I0005,共12页Kun-Ming Che Ming-Zu Zhang Jin-Lin He Pei-Hong Ni 
the National Natural Science Foundation of China(Nos.21975169 and 21374066);the Major Program of the Natural Science Project of Jiangsu Higher Education Institutions(No.15KJA150007);the Natural Science Foundation of Jiangsu Province(No.BK20171212);a Project Funded by the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions;Soochow-Waterloo University Joint Project for Nanotechnology from Suzhou Industrial Park.
The structure and properties of functional nanoparticles are important for stabilizing Pickering emulsion polymerization.Recently,cellulose nanocrystals(CNCs)are increasingly favored as a bio-based stabilizer for Pick...
关键词:Cellulose nanocrystals(CNCs) Polyphosphoesters(PPEs) Pickering emulsion Emulsion polymerization 
Functionalized Polyphosphoester via Living Ring-opening Polymerization and Photochemical Thiol-ene Click Reaction
《Chemical Research in Chinese Universities》2019年第2期340-344,共5页WANG Ying WANG Qiliao HOU Liman ZHOU Mingdong DONG Dewen ZHANG Ning 
Poly(ethylene phosphonate)was synthesized via the living ring-opening polymerization of cyclic phos-phonate monomer catalyzed by organocatalyst.The pendant vinyl ftmctionalities were employed to perform the pho-tochem...
关键词:Cyclic PHOSPHONATE RING-OPENING polymerization THIOL-ENE click reaction Post modification 
Reversal of paclitaxel resistance in human ovarian cancer cells with redox-responsive micelles consisting of a-tocopheryl succinate-based polyphosphoester copolymers被引量:5
《Acta Pharmacologica Sinica》2017年第6期859-873,共15页Feng-qian CHEN Jin-ming ZHANG Xie-fan FANG Hua YU Yu-ling LIU Hui LI Yi-tao WANG Mei-wan CHEN 
P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) is a major obstacle in achieving the therapeutic benefits of paclitaxel (PTX) in the treatment of human ovarian carcinoma. This study is aimed to develop...
关键词:ovarian carcinoma paclitaxel multidrug resistance NANOMEDICINES D-(x-tocopheryl succinate redox-responsive micelles P-gp apoptosis cell cycle arrest A2780/PTX cells 
Surface-modulated and thermoresponsive polyphosphoester nanoparticles for enhanced intracellular drug delivery被引量:2
《Science China Chemistry》2014年第4期579-585,共7页LI Yang WANG Feng SUN TianMeng DU JinZhi YANG XianZhu WANG Jun 
supported by the Ministry of Science and Technology of China(2010CB934001);the National Natural Science Foundation of China(51125012,51203145)
The chemical structure of end groups influenced the phase transition temperature of thermoresponsive polymers. We demonstrated a strategy for the preparation of the pH/thermo-responsive polymeric nanoparticles via sub...
关键词:THERMORESPONSIVE drug release POLYPHOSPHOESTER drug resistance 
Multiresponsive Polymer Assemblies Achieved by a Subtle Chain Terminal Modification
《Chinese Journal of Chemistry》2014年第1期51-56,共6页Weiwei Liu Yucai Wang Yang Li Feng Wang Xianzhu Yang Tianmeng Sun Jinzhi Du Jun Wang 
This work was supported by the Ministry of Science and Technology of China (Nos.2010CB934001,2012AA022501,2013CB933900),the National Natural Science Foundation of China (Nos.51203145,51125012),the Fundamental Research Funds for the Central Universities (No.WK2070000008) and the Open Project of State Key Laboratory of Supramolecular Structure and Materials (No.SKLSSM201301).
Inspired by the influence of chemical structure of end groups on the phase transition temperature of thermoresponsive polymers,we demonstrated a strategy to control the multi-responsiveness of polymer assemblies via s...
关键词:multi-responsive THERMORESPONSIVE PHASE-TRANSITION POLYPHOSPHOESTER 
Synthesis and Characterization of UPPE-PLGA-rhBMP2 Scaffolds for Bone Regeneration被引量:1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2012年第4期563-570,共8页田志超 朱元莉 邱进俊 关邯峰 李亮宇 郑守超 董学海 肖骏 
supported by a grant from the Scientific and Technological Project of Wuhan,China (No. 200960223069)
A novel unsaturated polyphosphoester(UPPE) was devised in our previous research,which is a kind of promising scaffold for improving bone regeneration.However,the polymerization process of UPPE scaffolds was unfavorabl...
关键词:poly(lactic-co-glycolic acid) microspheres bone morphogenetic protein-2 unsaturated polyphosphoester bone regeneration 
Syntheses of amphiphilic biodegradable copolymers of poly(ethyl ethylene phosphate) and poly(3-hydroxybutyrate) for drug delivery被引量:10
《Science China Chemistry》2009年第7期961-968,共8页CHENG Jing1 & WANG Jun2 1 Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China 2 Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China 
Supported by the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No.20060358036)
Biodegradable and amphiphilic triblock copolymers poly(ethyl ethylene phosphate)-poly(3-hydroxybutyrate)-poly(ethyl ethylene phosphate) (PEEP-b-PHB-b-PEEP) have been successfully synthesized through ring-opening polym...
关键词:poly(3-hydroxybutyrate) POLYPHOSPHOESTER drug delivery polymeric nanoparticles 
In Vitro Cytotoxicity of Polyphosphoester as a Novel Injectable Alveolar Replacement Material被引量:3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2008年第5期604-607,共4页张智星 毛靖 冯祥礼 肖建中 邱进俊 
a grant from the National High Technology Research and Development Program of China (863 Program, No. 2006AA03Z0443)
The aim of this study was to investigate the in vitro cytotoxicity of polyphosphoester polymer used as a novel injectable alveolar bone substitutes for controlled delivery of tetracycline. Cell culture medium was expo...
关键词:POLYPHOSPHOESTER CYTOTOXICITY MTT assay Alamar Blue test 
Composition and Structure of Fibrous Hydroxyapatite Growth on an Injectale Bone Tissue Engineering Scaffolds Material
《Journal of Wuhan University of Technology(Materials Science)》2005年第B12期159-162,共4页邱进俊 刘承美 
Fibrous hydroxyapatite ( HA ) wns grown upwards from the crosslinked unsaturated polyphosphoester( UPPE ) which was used us an injectable bone tissue engineering scaffolds. Composition of fibrous HA was determine...
关键词:fibrous hydroxyapatite unsaturated polyphosphoester BONE tissue engineering 
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