This work was supported by the grants from the National Natural Science Foundation of China (30730054, 30572119, 30670937, 30971279, 30901363), the Hi-tech Research and Development Program of China from Ministry of Science and Technology (2007AA02Z120), the Ministry of Education (20060486008, 20090141120011), Provincial Department of Science and Tech- nology of Hubei (2007ABC010), Provincial Department of Health of Hubei (JX4B14), Innovation Program of Wuhan Uni- versity for Young Scholars (WU3082007), National Innovation Experiment Program for College Students (WU2007061), China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China (Chang Jiang Scholar TJ).
Type I natural killer T cells (NKT cells), a subset of CDld-restricted T cells with invariant Vαβ TCR, are characterized by prompt production of large amounts of Thl and/or Th2 cytokines upon primary stimulation t...
Acknowledgements This work was supported by the grants from the National Natural Science Foundation of China (30730054, 30572119, 30670937, 30971279, 30901363), the Hi-tech Research and Development Program of China from Ministry of Science and Technology (2007AA02Z120), the Ministry of Education (20060486008), National Innovation Experiment Program for College Students (WU2007061), Provincial Departrnent of Science and Technology of Hubei (2007ABC010), China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China (Chang Jiang Scholar T.J.).
CD8^+ natural killer T (NKT) cells from EBV-associated tumour patients are quantitatively and functionally impaired. EBV-induced CD8^+ NKT cells drive syngeneic T cells into a Thl-bias response to suppress EBV-ass...