国家自然科学基金(30572119)

作品数:4被引量:14H指数:2
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相关作者:吴静杨大明蒋艳萍王俐陈朗更多>>
相关机构:监利县人民医院武汉大学暨南大学更多>>
相关期刊:《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《中国公共卫生》《武汉大学学报(医学版)》更多>>
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相关领域:农业科学医药卫生环境科学与工程生物学更多>>
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3种流感病毒细胞毒T淋巴细胞抗原表位比较
《中国公共卫生》2010年第10期1293-1294,共2页王飞鹏 何贤辉 
国家自然科学基金(30572119和30371651)
关键词:流感病毒 抗原表位 表位预测 交叉抗原反应 
Type I natural killer T cells: naturally born for fighting被引量:9
《Acta Pharmacologica Sinica》2010年第9期1123-1132,共10页Jin-quan TAN Wei XIAO Lan WANG Yu-ling HE 
This work was supported by the grants from the National Natural Science Foundation of China (30730054, 30572119, 30670937, 30971279, 30901363), the Hi-tech Research and Development Program of China from Ministry of Science and Technology (2007AA02Z120), the Ministry of Education (20060486008, 20090141120011), Provincial Department of Science and Tech- nology of Hubei (2007ABC010), Provincial Department of Health of Hubei (JX4B14), Innovation Program of Wuhan Uni- versity for Young Scholars (WU3082007), National Innovation Experiment Program for College Students (WU2007061), China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China (Chang Jiang Scholar TJ).
Type I natural killer T cells (NKT cells), a subset of CDld-restricted T cells with invariant Vαβ TCR, are characterized by prompt production of large amounts of Thl and/or Th2 cytokines upon primary stimulation t...
关键词:NKT cells tumor immunity cell development and homeostasis Th1/Th2 cytokines 
EBV-Induced Human CD8^+ NKT Cells Synergise CD4^+ NKT Cells Suppressing EBV-Associated Tumours upon Induction of Thl-Bias被引量:5
《Cellular & Molecular Immunology》2009年第5期367-379,共13页Wei Xiao Li Li Rui Zhou Ruijing Xiao Yujuan Wang Xiang Ji Mengjun Wu Lan Wang Wei Huang Xiaoling Zheng Xinti Tan Lang Chen Tao Xiong Jie Xiong Youxin Jin Jinquan Tan Yuling He 
Acknowledgements This work was supported by the grants from the National Natural Science Foundation of China (30730054, 30572119, 30670937, 30971279, 30901363), the Hi-tech Research and Development Program of China from Ministry of Science and Technology (2007AA02Z120), the Ministry of Education (20060486008), National Innovation Experiment Program for College Students (WU2007061), Provincial Departrnent of Science and Technology of Hubei (2007ABC010), China, and Chang Jiang Scholars Program from Ministry of Education, China and Li Ka Shing Foundation, Hong Kong, China (Chang Jiang Scholar T.J.).
CD8^+ natural killer T (NKT) cells from EBV-associated tumour patients are quantitatively and functionally impaired. EBV-induced CD8^+ NKT cells drive syngeneic T cells into a Thl-bias response to suppress EBV-ass...
关键词:CD8^+ NKT cells EBV human-thymus-SCID chimaeras IFN-γ 
Syk或ZAP-70信号途径诱导脐带血CD4^+T细胞极化
《武汉大学学报(医学版)》2008年第3期283-286,297,I0001,共6页蒋艳萍 杨大明 吴静 陈朗 王俐 谭锦泉 
国家自然科学基金资助项目(编号:30572119)
目的:探讨IL-2或IL-4和基质细胞源因子(SDF)-1α协同刺激下,脐带血CD4+T细胞极化的作用及其与非受体型蛋白质酪氨酸激酶的关系。方法:流式细胞术、实时定量RT-PCR检测IL-2或IL-4和SDF-1α协同刺激下,CD4+T细胞中胞内Th1型和Th2型细胞因...
关键词:白细胞介素-2 白细胞介素-4 基质细胞源因子-1α 非受体型蛋白酪氨酸激酶 反义肽核酸 
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