This work was supported by grants from the National Basic Research Program(973 Program,2009CB918903);863 Project of the Ministry of Science and Technology of China(2007AA02Z115);NSFC(90919032,30970562,30670441,30811130394 and 30870562);Tianjin Municipal Science and Technology Commission(08ZCGHHZ01900 and 08JCYBJC07700);Specialized Fund for the Doctoral Program of Higher Education(20091202110001);Tianjin Educational Committee Foundation(2008ZD01).
The multifunctional protein p100 is a vital transcriptional regulator that increases gene transcription by forming a physical bridge between promoter-specific transcription factors and the basal transcription machiner...