This study was supported by grants from the National Natural Science Foundation of China (No. 30470776) and the Beijing Natural Science Foundation (No. 7082102). Part of this paper was accepted for poster presentation at the First Asian Neurogastroenterology and Motility Association (ANMA) 2009, Seoul, Korea.Acknowledgements: The authors world like to thank Prof. ZHENG Zhen-hui for establishment of animal models and Ms. CHEN Li for histological technique.
Background Mast cells are implicated in the development of irritable bowel syndrome (IBS), which is associated with the activation of the "neural-immune" system. The aim of this study was to investigate the role o...