Insomnia is currently a common phenomenon,which manifests itself as difficulty in falling asleep,problems remaining asleep,or early awakening,and has a serious impact on people’s lives.Neurotransmitters play a key ro...
Asthma is one of the most common chronic respiratory pathologies worldwide. The cost of its treatment, particularly for populations in developing countries like Senegal, requires an alternative which consists of devel...
supported by grants from Hong Kong Research Grant Committee(14100619,RIF/R4005-18F)and Innovation and Technology Fund ITS/212/21.
Endothelium-dependent contraction(EDC)exists in blood vessels of normotensive animals,but is exaggerated in hypertension.An early signal in EDC is cytosolic Ca2+rise in endothelial cells.In this study we investigated ...
supported by the National Natural Science Foundation of China(No.32371505);the Innovation Fund Project of the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences(Nos.DMU-1&DICP UN202204,DICPI202110).
Acetylcholine(ACh)is a common neurotransmitterl)that is secreted by cholinergic neurons[2]and is found mainly in the peripheral and central nervous systems.[3]ACh transmits nerve signals from presynaptic to postsynapt...
funded by research grants from the Canadian Institutes of Health(CIHR):MOP 89825,EKL;PRJ153101,EKL and JM;support of a CIHR Banting and Best Canada Graduate Scholarship and an Ontario Graduate Scholarship,SKP.
Background Cognitive reserve allows for resilience to neuropathology,potentially through active compensation.Here,we examine ex vivo electrophysiological evidence for active compensation in Alzheimer’s disease(AD)foc...
BACKGROUND Although the spasm provocation test(SPT)can diagnose coronary spasms,it would be helpful if it could also predict their occurrence.AIM To investigate whether coronary spasms can be predicted using changes i...
National Natural Science Foundation of China,Nos.82003 729 (to Ying W),82022071 (to YiW);Natural Science Foundation of Shandong Province of China,No.ZR2020QH357 (to Ying W);Public Welfare Technology Research Program of Zhejiang Province,No.LGF20H09001 1 (to JF)。
Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal scle rosis.There is no effective treatment for cognitive impairment.Medial septum cholinergic neurons have ...
This work was supported by grants from the National Natural Science Foundation of China(31872280 and 31622054);the Strategic Priority Research Program of the Chinese Academy of Science(XDB11010800);the China Postdoctoral Science Foundation(E290D51135),and the Chinese Academy of Sciences(E129Q21105).
Females increase aggression for mating opportunities and for acquiring reproductive resources.Although the close relationship between female aggression and mating status is widely appreciated,whether and how female ag...
Parkinson’s disease is the most common movement disorder,affecting about 1%of the population over the age of 60 years.Parkinson’s disease is characterized clinically by resting tremor,bradykinesia,rigidity and postu...
Researchers have identified a novel function of acetylcholine produced by spleen fibroblastic reticular cells(FRCs)in driving autoimmune responses in systemic lupus erythematosus(SLE),according to a new study publishe...