MICRODIALYSIS

作品数：63被引量：190H指数：8
导出分析报告
相关领域：医药卫生更多>>
相关作者：吴蔚然马兰李浩洪朱子涛康林更多>>
相关机构：中国医学科学院北京协和医学院复旦大学上海医学院中国科学院四川大学华西医院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划上海市教育委员会重点学科基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Nebulized aminoglycosides for ventilator-associated pneumonia:Methodological considerations and lessons from experimental studies
《Journal of Intensive Medicine》2025年第1期12-22,共11页Jean-Jacques Rouby Jing Xia Jayesh Dhanani Gianluigi Li Bassi Antoine Monsel Antoni Torres on behalf of the European Investigators Network for Nebulized Antibiotics in Ventilator-associated Pneumonia(ENAVAP) 
Aminoglycosides are concentration-dependent antibiotics exerting a bactericidal effect when concentrations at the site of infection are equal to or greater than 5 times the minimum inhibitory concentrations(MIC).When ...
关键词：AMINOGLYCOSIDES Ventilator-associated pneumonia Nebulized amikacin Nebulized tobramycin Lung microdialysis Experimental intensive care unit 
Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy被引量：1
《Neural Regeneration Research》2023年第11期2459-2465,共7页Junzi Chen Yu Wang Cong Chen Qingyang Zhang Shuang Wang Yi Wang Jiajia Fang Ying Wang 
National Natural Science Foundation of China,Nos.82003 729 (to Ying W),82022071 (to YiW);Natural Science Foundation of Shandong Province of China,No.ZR2020QH357 (to Ying W);Public Welfare Technology Research Program of Zhejiang Province,No.LGF20H09001 1 (to JF)。
Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal scle rosis.There is no effective treatment for cognitive impairment.Medial septum cholinergic neurons have ...
关键词：ACETYLCHOLINE cholinergic neuron cognitive deficit diffusion tensor imaging hippocampal sclerosis HIPPOCAMPUS medial septum MICRODIALYSIS OPTOGENETICS temporal lobe epilepsy 
Comparative study on brain pharmacokinetics of Buyang Huanwu Decoction in normal and cerebral ischemia rats using brain microdialysis combined with LC-MS/MS被引量：4
《Chinese Herbal Medicines》2022年第4期630-637,共8页Wanyi Liu Keqi Zeng Xin Zhou Yingfeng Zhang Cong Nie 
supported by the National Natural Science Foundation of China(No.81873227)。
Objective To conduct a comparative study on the brain pharmacokinetics of seven ingredients(i.e.senkyunolide A,ferulic acid,formononetin,calycosin,ononin,calycosin-O-β-D-glucopyranoside,and paeoniflorin),which were t...
关键词：brain pharmacokinetics Buyang Huanwu Decoction cerebral ischemia LC-MS/MS MICRODIALYSIS 
Influence of anastomoses on intestine ischemia and cefuroxime concentrations:Evaluated in the ileum and colon in a porcine model
《World Journal of Gastrointestinal Pathophysiology》2021年第1期1-13,共13页Pelle Hanberg Mats Bue Maja Thomassen Uffe Schou Løve Josephine Olsen Kipp Christina Harlev Elisabeth Petersen Kjeld Søballe Maiken Stilling 
BACKGROUND Anastomotic leakage is a serious complication following gastrointestinal surgery and is associated with increased morbidity and mortality.The incidence of anastomotic leakage is determined by anatomy and is...
关键词：ANASTOMOSIS CEFUROXIME COLON ILEUM Ischemic metabolites MICRODIALYSIS 
Dynamic Cerebral Microdialysis during Pallidotomy and Thalamotomy in Parkinson’s Disease: A Preliminary Neurochemical Study
《Open Journal of Modern Neurosurgery》2020年第2期284-296,共13页Sergio A. Sacchettoni Juan P. Abud Napoleon Torres Yngo García Daniel A. Onay Juan Luis Rodulfo Juan Félix Del Corral Pedro Rada Rafael Galera Luis Hernández 
In Parkinson’s disease (PD), dopaminergic neurons reduce the regulation of glutamatergic (glutamate-Glu) input from the cortex to neostriatum (caudate and putamen nuclei) consequently leading to a hyperactivity of gl...
关键词：CEREBRAL MICRODIALYSIS Parkinson’s Disease PALLIDOTOMY THALAMOTOMY Basal GANGLIA Circuit CEREBRAL ELECTROMODULATION DBS 
Pharmacokinetics of different dosage of astragalus membranaceus of buyang huanwu decoction in rats with cerebral ischemic injury by microdialysis combined with LC/MS被引量：5
《Journal of Chinese Pharmaceutical Sciences》2020年第2期90-101,共12页Shengxin Wang Xiangli Yan Haozhen Zheng Jianye Yu Aiming Yu Xiao Shen Lisheng Wang 
National Natural Science Foundation of China(Grant No.81373973,81573872,81873228);Science and Technology Planning Project of Guangdong Province(Grant No.2017KZDXM018).
To investigate the pharmacokinetics of effective components of Bu Yang Huang Wu Decoction(BYHWD)with different dosages of Astragalus(Yiqi groups and Huoxue groups)applicating in rats with middle cerebral artery occlus...
关键词：Bu Yang Huan Wu Tang PHARMACOKINETICS MICRODIALYSIS Cerebral ischemia-reperfusion 
Purines Change at Acupoints along the Pericardium Meridian in Healthy and Myocardial Ischemic Rats被引量：3
《Chinese Journal of Integrative Medicine》2019年第4期285-291,共7页ZHOU Yu-mei ZHUANG Yi CAI Ding-jun LV Pei-ran ZHOU Jie WAN Min REN Yu-lan LIANG Fan-rong 
Supported by National Natural Science Foundation of China(No.81590951,81373559,81373561 and 81573885);the State Key Program for Basic Research of China(No.2012CB518501);the Project of the Second Clinical Medical College of Nanjing University of Chinese Medicine(No.RLZZ201605)
Objective: To quantify the purine concentrations of the acupoints along the pericardium and nonpericardium meridians under healthy and myocardial ischemia conditions to investigate the relationship between acupoint pu...
关键词：acupoint MYOCARDIAL ischemia PERICARDIUM meridian PURINE adenosine MICRODIALYSIS high-performance liquid chromatography 
Monitoring unbound warfarin in drug combination therapy by pharmacokinetics and fluorospectrometry被引量：1
《Chinese Herbal Medicines》2019年第1期92-97,共6页Jia-ding Guo Ying-yue Zhang Yan Huo Yan-xu Chang Er-wei Liu Jia Hao 
supported by Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_14R41);Tianjin Research Program of Application Foundation and Advanced Technology(15JCYBJC29300)
Objective: Monitoring the unbound drug concentration in blood in combination therapy is necessary,because its concentration determines the efficacy of drug therapy. This study was designed to explore the effect of Dan...
关键词：Dan Hong INJECTION fluorospectrometry MICRODIALYSIS PHARMACOKINETICS unbound WARFARIN 
Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions被引量：1
《Journal of Pharmaceutical Analysis》2018年第6期407-412,共6页Jayesh A.Dhanani Suzanne L.Parker Jeffrey Lipman Steven C.Wallis Jeremy Cohen John Fraser Adrian Barnett Michelle Chew Jason A.Roberts 
funded by the TPCH foundation grant (MS201140);the RBWH foundation grant 2012;funding from the Australian National Health and Medical Research Council for a Centre of Research Excellence (APP1099452);funded in part by a Practitioner Fellowship (APP1117065) from the National Health and Medical Research Council of Australia
Microdialysis is a technique used to measure the unbound antibiotic concentration in the interstitial spaces, the target site of action. In vitro recovery studies are essential to calibrating the microdialysis system ...
关键词：MICRODIALYSIS COMBINATION antibiotic therapy Relative recovery rate PHARMACOKINETICS ANTI-INFECTIVES Protein BINDING 
Microdialysis in awake macaque monkeys for central nervous system pharmacokinetics被引量：2
《Animal Models and Experimental Medicine》2018年第4期314-321,共8页Thibaud Thiollier Caisheng Wu Gregory Porras Erwan Bezard Qin Li Jinlan Zhang Hugues Contamin 
Background: The brain bioavailability of novel small molecules developed to address central nervous system disease is classically documented through ex vivo or in vivo analyses conducted in rodent models. Data acquire...
关键词：AWAKE bioavailability blood BRAIN barrier BRAIN central nervous system crossing methods MICRODIALYSIS non-human PRIMATE PHARMACOKINETIC 
全选清除导出
共7页<1234567>
检索报告 对象比较 聚类工具 使用帮助 返回顶部