PRIMATE

作品数：94被引量：159H指数：7
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相关机构：中国科学院大学北京大学中国科学技术大学澳大利亚国立大学更多>>
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The role of primate-specifc genes in the phenotypicevolution of lorises
《Current Zoology》2025年第2期267-272,共6页Chunyan Chen Yong Shao Sheng Wang Mingli Li Haifa Qiao 
supported by the Shaanxi FundamentalScience Research Project for Chemistry&Biology(grant no.22JHQ049);Basic Research Program of Natural Sciencesof Shaanxi Province(2019JM-339).
Pygmy lorises are arboreal primates primarily found in forest environments across Southeast Asia(Nekaris 2014).Theyhave a diverse diet,including plant secretions,nectar,fruits,invertebrates,tree bark,and bird eggs.All...
关键词：primate specific genes pygmy lorises southeast asia arboreal primates plant secretionsnectarfruitsinvertebratestree phenotypic characteristics phenotypic evolution 
Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles
《Neural Regeneration Research》2025年第4期1124-1134,共11页Yanting Liu Wei Huang Jiayi Wen Xin Xiong Ting Xu Qi Wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li Weili Yang 
supported by the National Natural Science Foundation of China,Nos.32070534(to WY),32370567(to WY),82371874(to XL),81830032(to XL),82071421(to SL);Key Field Research and Development Program of Guangdong Province,No.2018B030337001(to XL);Guangzhou Key Research Program on Brain Science,No.202007030008(to XL);Department of Science and Technology of Guangdong Province,Nos.2021ZT09Y007,2020B121201006(to XL);Guangdong Basic and Applied Basic Research Foundation,Nos.2022A1515012301(to WY),2023B1515020031(to WY).
The vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal degeneration.However,it remains largely unclear how PINK1 and Parkin a...
关键词：NEURODEGENERATION PARKIN Parkinson’s disease PINK1 subcellular distribution 
Continuous immunosuppression is required for suppressing immune responses to xenografts in non‑human primate brains
《Cell Regeneration》2024年第1期305-314,共10页Su Feng Ting Zhang Zhengxiao He Wenchang Zhang Yingying Chen Chunmei Yue Naihe Jing 
National Key Basic Research and Development Program of China(2019YFA0801402,2018YFA0107200,2018YFA0801402,2018YFA0800100);Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020501,XDA16020404);National Natural Science Foundation of China(32130030,31900454).
Continuous immunosuppression has been widely used in xenografts into non-human primate brains.However,how immune responses change after transplantation in host brains under continuous immunosuppressive adminis-tration...
关键词：Cell transplantation XENOGRAFT Immune response Non-human primate brain Human induced neural stem/progenitor cells(iNPCs) 
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging被引量：1
《Protein & Cell》2024年第8期612-632,共21页Qinchao Hu Bin Zhang Yaobin Jing Shuai Ma Lei Hu jingyi Li Yandong Zheng Zijuan Xin Jianmin Peng Si Wang Bin Cheng Jing Qu Weiqi zhang Guang-Hui Liu Songlin Wang 
Aging has a profound impact on the gingiva and significantly increases its susceptibility to periodontitis,a worldwide prevalent inflammatory disease.However,a systematic characterization and comprehensive understandi...
关键词：single-nucleus RNA-sequencing PRIMATE GINGIVA AGING YAP 
Feedback processing in the primate brain and in AI systems
《Science China(Technological Sciences)》2024年第8期2297-2309,共13页JIANG Yong HE Sheng 
supported by the National Key Research and Development Program of China (Grant Nos. 2021ZD0204200, and 2021ZD0203800);the Key Research Program of Frontier Sciences, Chinese Academy of Sciences (Grant No. KJZDSW-L08);CAS Project for Young Scientists in Basic Research (Grant No. YSBR-071)。
The primate brain and artificial intelligence(AI) can both be conceptualized as information processing systems, each with its own distinct biological and computational architectures. While there are parallels between ...
关键词：cognitive neuroscience artificial intelligence feedback processing ATTENTION LEARNING 
Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics被引量：1
《Protein & Cell》2024年第5期364-384,共21页Huifen Lu Ying Jing Chen Zhang Shuai Ma Weiqi Zhang Daoyuan Huang Bin Zhang Yuesheng Zuo Yingying Qin Guang-Hui Liu Yang Yu Jing Qu Si Wang 
This work was supported by the National Natural Science Foundation of China(Grant Nos.82122024,92149301,82125011,81921006);the National Key Research and Development Program of China(2022YFA1103700,2020YFA0804000,2020YFA0112200,2021YFF1201000,the STI2030-Major Projects-2021ZD0202400);the National Natural Science Foundation of China(Grant Nos.92168201,82225019,91949209,92049304,82071588,82322025,32000500,82271600,92049116,32121001,82192863,82201714);CAS Project for Young Scientists in Basic Research(YSBR-076,YSBR-012);the Strategic Collaborative Research Program of the Ferring Institute of Reproductive Medicine,Ferring Pharmaceuticals and the Chinese Academy of Sciences(FIRMC180305);the Program of the Beijing Natural Science Foundation(Z230011);the Informatization Plan of Chinese Academy of Sciences(CAS-WX2021SF-0301,CAS-WX2022SDC-XK14,CAS-WX2021SF-0101);New Cornerstone Science Foundation through the XPLORER PRIZE(2021-1045);Youth Innovation Promotion Association of CAS(2022083,E1CAZW0401);Excellent Young Talents Program of Capital Medical University(12300927);the Project for Technology Development of Beijing-affiliated Medical Research Institutes(11000023T000002036310);Excellent Young Talents Training Program for the Construction of Beijing Municipal University Teacher Team(BPHR202203105);Young Elite Scientists Sponsorship Program by CAST(2021QNRC001);The Fellowship of China Postdoctoral Science Foundation(2022M712216).
The ovary is indispensable for female reproduction,and its age-dependent functional decline is the primary cause of infertility.However,the molecular basis of ovarian aging in higher vertebrates remains poorly underst...
关键词：spatial transcriptome PRIMATE OVARY AGING SENESCENCE inflammation 
Multimodal Nature of the Single-cell Primate Brain Atlas:Morphology,Transcriptome,Electrophysiology,and Connectivity
《Neuroscience Bulletin》2024年第4期517-532,共16页Yuhui Shen Mingting Shao Zhao-Zhe Hao Mengyao Huang Nana Xu Sheng Liu 
supported by the Natural Science Foundation of China(81961128021 and 82371095);the National Key R&D Program of China(2022YEF0203200);the Guangdong Provincial Key R&D Programs(2018B030335001);the Science and Technology Program of Guangzhou(202007030011 and 202007030010).
Primates exhibit complex brain structures that augment cognitive function.The neocortex fulfills high-cognitive functions through billions of connected neurons.These neurons have distinct transcriptomic,morphological,...
关键词：NEURON Brain atlas Patch-seq CONNECTIVITY PRIMATE 
Comparative analysis of primate and pig cells reveals primate-specific PINK1 expression and phosphorylation被引量：1
《Zoological Research》2024年第2期242-252,共11页Xiu-Sheng Chen Rui Han Yan-Ting Liu Wei Huang Qi Wang Xin Xiong Ying Zhang Jian-Guo Zhao Shi-Hua Li Xiao-Jiang Li Wei-Li Yang 
supported by the National Natural Science Foundation of China (32070534,32370567,82371874,81830032,31872779,82071421,81873736);Key Field Research and Development Program of Guangdong Province (2018B030337001);Guangzhou Key Research Program on Brain Science (202007030008);Department of Science and Technology of Guangdong Province (2021ZT09Y007,2020B121201006);Guangdong Basic and Applied Basic Research Foundation (2023B1515020031,2022A1515012301);Fundamental Research Funds for the Central Universities (Jinan University,21620358)。
PTEN-induced putative kinase 1(PINK1),a mitochondrial kinase that phosphorylates Parkin and other proteins,plays a crucial role in mitophagy and protection against neurodegeneration.Mutations in PINK1 and Parkin can l...
关键词：PINK1 PARKIN MITOCHONDRIA PHOSPHORYLATION Non-human primates PIGS 
Erratum to: Born to sing! Song development in a singing primate
《Current Zoology》2024年第2期276-276,共1页Chiara De Gregorio Filippo Carugati Vittoria Estienne Daria Valente Teresa Raimondi Valeria Torti Longondraza Miaretsoa Jonah Ratsimbazafy Marco Gamba Cristina Giacoma 
The pagination of this article online has been updated to pages 597-608 to match the print version.The Publisher sincerely apologizes for introducing this error online.
关键词：introducing sincerely MATCH 
New Target for Delaying Primate Spinal Cord Aging
《Bulletin of the Chinese Academy of Sciences》2023年第4期238-239,共2页LIU Guanghui 
The spinal cord,a vital bridge connecting the brain and peripheral nerves,plays a pivotal role in governing motor functions and coordinating basic life activities of the body,mainly through a rare and critical group o...
关键词：connecting AUTONOMOUS CRITICAL 
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