This work was supported by the National Natural Science Foundation of China(Nos.91129727,81020108031,and 30973558);the Major Specialized Research Fund from the Ministry of Science and Technology in China(No.2009ZX09103-144).
Over the last 20 years,intensive research has been focused on the specific mechanisms mediating the pancreatic β-cell injury.Both the decreased viability and the dysfunction of β-cells have become the key factors in...