supported by the National Natural Science Foundation of China(Nos.30921065,30730003 and 30870058) to L.Huang;the Danish Research Council for Technology and Production(No.274-07-0116)
Topoisomerase III (topo III), a type IA topoisomerase, is widespread in hyperthermophilic archaea. In order to interrogate the in vivo role of archaeal topo III, we constructed and characterized a topo III gene dele...