《Digital Chinese Medicine》

作品数：268被引量：517H指数：9
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《Digital Chinese Medicine》
主办单位：湖南中医药大学;中华中医药学会
最新期次：2024年4期更多>>
发文主题：CHINESE_MEDICINETRADITIONAL_CHINESE_MEDICINEDIGITALTCMINSTRUCTIONS更多>>
发文领域：医药卫生文化科学自动化与计算机技术理学更多>>
发文作者：贺福元周逸群刘文龙罗悦温川飙更多>>
发文机构：湖南中医药大学中国中医科学院上海中医药大学江西中医药大学更多>>
发文基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Editorial Board of Digital Chinese Medicine
《Digital Chinese Medicine》2024年第4期F0002-F0002,共1页
Research progress in Fangjiomics:methodologies,applications,and perspectives
《Digital Chinese Medicine》2024年第4期309-319,共11页LI Bing ZHAO Yuwen NIU Qikai WANG Zhong 
National Key Research and Development Project(2023YFC3502903);National Natural Science Foundation of China(82474376);Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2023C063YLL).
Fangjiomics is a promising paradigm that enhances research on multi-omics-based pharmacological mechanisms of Fangji from holistic and systematic perspective.We reviewed recent advances in Fangjiomics,focusing on data...
关键词：Fangjiomics Multi-omics data Compatibility of prescription Fangji database Network pharmacology 
Integrating proteomics and targeted metabolomics to reveal the material basis of liver-gallbladder damp-heat syndrome in chronic hepatitis B
《Digital Chinese Medicine》2024年第4期320-331,共12页LI Ni’ao GONG Yuefeng WANG Jia CHEN Qingqing SU Shibing ZHANG Hua LU Yiyu 
National Natural Science Foundation of China(82274183);Shanghai Municipal Health Commission’s special clinical research project in the health industry(202240243);Science and Technology Innovation Program of Science and Technology Commission of Shanghai Municipality(STCSM)(20ZR1453700).
Objective To elucidate the biological basis of liver-gallbladder damp-heat syndrome(LGDHS)within the framework of traditional Chinese medicine(TCM)as a complementary diagnostic and therapeutic approach in chronic hepa...
关键词：Liver-gallbladder damp-heat syndrome(LGDHS) Chronic hepatitis B(CHB) PROTEOMICS Targeted metabolomics Molecular mechanism Biomarkers 
The modulating of Qingguang’anⅡFormula on gut microbiota in mice with chronic high intraocular pressure by 16S rDNA sequencing
《Digital Chinese Medicine》2024年第4期332-342,共11页ZHOU Yasha GAO Wenyong HUANG Yu XIA Xin XIAO Li DENG Ying PENG Qinghua PENG Jun 
National Natural Science Foundation of China(81904260);Scientific Research Project of Hunan Province Department of Education(22B0398);Scientific Research Project of Traditional Chinese Medicine of Hunan Province(D2022045).
Objective To investigate the effects of Qingguang'anⅡFormula(QGAⅡ)on the gut micro-biota of mice with chronic high intraocular pressure(IOP)model,and explore its key micro-biota for protecting the optic nerve.Method...
关键词：Qingguang’anⅡFormula Chronic high intraocular pressure 16S rDNA sequencing Optic neuroprotection Gut microbiota 
TCMLLM-PR:evaluation of large language models for prescription recommendation in traditional Chinese medicine
《Digital Chinese Medicine》2024年第4期343-355,共13页TIAN Haoyu YANG Kuo DONG Xin ZHAO Chenxi YE Mingwei WANG Hongyan LIU Yiming HU Minjie ZHU Qiang YU Jian ZHANG Lei ZHOU Xuezhong 
National Key Research and Development Program(2023YFC3502604);National Natural Science Foundation of China(U23B2062 and 82374302).
Objective To develop and evaluate a fine-tuned large language model(LLM)for traditional Chinese medicine(TCM)prescription recommendation named TCMLLM-PR.Methods First,we constructed an instruction-tuning dataset conta...
关键词：Large language models Instruction-tuning Prescription recommendation Traditional Chinese medicine(TCM) Assisted decision-making 
Classification of cold and hot medicinal properties of Chinese herbal medicines based on graph convolutional network
《Digital Chinese Medicine》2024年第4期356-364,共9页YANG Mengling LIU Wei 
Hunan Provincial Natural Science Foundation(2022JJ30438);Natural Science Foundation of Changsha(kq2202260);Hunan Province Traditional Chinese Medicine Research Project(B2023039).
Objective To develop a model based on a graph convolutional network(GCN)to achieve ef-ficient classification of the cold and hot medicinal properties of Chinese herbal medicines(CHMs).Methods After screening the datas...
关键词：Chinese herbal medicine Cold and hot medicinal properties Molecular descriptor Graph convolutional network(GCN) Medicinal property classification 
Recent advancements in digital and traditional treatment strategies for major depressive disorder using medicinal herbs
《Digital Chinese Medicine》2024年第4期365-387,共23页Manasi Khadanga Nihar Ranjan Kar Nityananda Sahoo Bichitrananda Tripathy 
Integrating digital health technologies,including mobile applications and digital biomarkers,with traditional medicinal plants and phytochemicals may enhance the effectiveness of standard antidepressants.Mechanisms th...
关键词：FLUOXETINE Major depressive disorder(MDD) PHYTOMEDICINE Neurological disorders DEPRESSION Digital health 
Harnessing traditional herbal medicine:molecular insights into diabetic wound healing for modern therapeutics
《Digital Chinese Medicine》2024年第4期388-404,共17页Pavithra Bharathy Punniyakoti Veeraveedu Thanikachalam 
This study aims to explore the molecular aspects of the wound-healing potential of medicinal plants through preclinical and clinical research.This review focuses on the theoretical sup-port and therapeutic effects of ...
关键词：Herbal remedies Diabetic wound healing Pharmacological studies Vascular endothelial growth factor(VEGF) Tumor necrosis factor(TNF)-α Nuclear factor kappa B(NF-κB) Transforming growth factor(TGF)-β1 HYDROXYPROLINE 
Uric acid-lowering activity and mechanisms of Chinese medicines with medicinefood homology:a systematic study
《Digital Chinese Medicine》2024年第4期405-418,共14页QIN Fengyi ZHU Yishuo ZHAO Lewei CHEN Siyu QING Zhixing 
National Key R&D Program of China(2021YFD 1600301 and 2021YFD1600105);Hunan Provincial Key Research and Development Project(2023NK2041).
Objective To summarize the uric acid-lowering effects and mechanisms of Chinese medicines with medicine-food homology,aiming to provide novel perspectives for the devel-opment of new anti-hyperuricemia(HUA)drugs.Metho...
关键词：Hyperuricemia(HUA) Medicine food homology Chinese medicine Active compounds EXTRACT 
Risk assessment of coronary artery occlusion based on integrated Chinese and western medicine data
《Digital Chinese Medicine》2024年第4期419-428,共10页ZHANG Jiyu XU Jiatuo TU Liping WANG Yu 
National Natural Science Foundation of China(82104738);High-Level Key Discipline Construction Project in Traditional Chinese Medicine Diagnostics by the National Administration of Traditional Chinese Medicine(ZYYZDXK-2023069);Clinical Research Project in the Health Industry by Shanghai Municipal Health Commission(20244Y0129).
Objective To develop an integrated risk model for coronary artery occlusion based on data of both traditional Chinese medicine(TCM)and western medicine data,and to evaluate the contribution of TCM-specific indicators ...
关键词：Machine learning Coronary heart disease(CHD) Traditional Chinese medicine(TCM) Diagnosis Risk prediction Comprehensive risk model 
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