supported by the National Key Research and Development Program of China(2022YFC2604100,2022YFC2302900,2021YFC2301400,and 2022YFE0131700);National Natural Science Foundation of China(92169208,32222031,82071813,32141004,and 82171775);Peking University People’s Hospital Research and Development Funds(RDGS2022-05);National Postdoctoral Program for Innovative Talents of China(BX20220332)。
Studies have focused on neutralizing antibody titers and T-cell activation induced by vaccination against different SARS-CoV-2strains[1,2].Advanced single-cell technology has allowed for a comprehensive evaluation of ...
Capital Health Development Research Project,Grant/Award Number:2022-2-2093;Beijing Research Ward Construction Demonstration Unit Project,Grant/Award Number:BCRW202101;National Natural Science Foundation of China,Grant/Award Number:82270133;Beijing Municipal Scienceand Technology Commission,Grant/Award Number:Z221100007422067。
Importance:It remained unclear that the efficacy comparison between low-dose immune tolerance induction(LD-ITI)incorporating immunosuppressants(IS)when severe hemophilia A(SHA)patients had inhibitor-titer≥200 Bethesd...
In a recent issue of Lancet Haematology,Xue et al1 reported an adeno-associated virus(AAV)-based gene therapy in 10 patients with hemophilia B(HB)from China.BBM-H901,a novel vector comprised of an engineered liver-tro...
supported by the National Key Research and Development Program of China(2019YFA0905000);the National Natural Science Foundation of China(21871085 and 31971380);the Fundamental Research Funds for the Central Universities(222201714026).
Taxadiene is an important precursor for the biosynthesis of highly effective anticancer drug paclitaxel,but its microbial biosynthesis yield is very low.In this study,we employed Yarrowia lipolytica as a microbial hos...
supported by grants from the Key R&D Program of the Xinjiang Autonomous Region,China(2021b02002-2);the National Natural Science Foundation of China(31960538)。
Identifying the sex pheromone systems of local pest populations facilitates their management,especially for moth species that show significant geographic variation in sex pheromone communication.We investigated the ph...
We thank the Foundation of State Key Laboratory of NBC Protection for Civilian SKLNBC2018-03 and SKLNBC2020-02 for financial support.
Quantitative analysis is essential for virus research,especially in determining the virus titer.The classical method plaque assay is time-consuming,complex,and difficult for the phages that cannot form apparent plaque...
approved by Mochtar Riady Institute for Nanotechnology(MRIN),Tangerang,Banten Indonesia(Protocol No.2108017-03).
Background:Several vaccines have been approved against COVID-19,and 5 have been used in Indonesia.Due to the decrease in antibody levels 3 to 6 months after the second dose of CoronaVac,healthcare workers received the...
supported by the Ministry of Science and Technology of the People’s Republic of China(No.2020YFA0907703);the National Natural Science Foundation of China(Nos.32070044,32025002);the Biological Resources Programme,Chinese Academy of Sciences(No.KFJ-BRP-009)。
Natural cyclohexapeptide AFN A_(1) from Streptomyces alboflavus 313 has moderate antibacterial and antitumor activities.An artificial designed AFN A_(1) homodimer,di-AFN A_(1),is an antibiotic exhibiting 10 to 150 fol...
Objective To explore whether prophylactic anti-viral therapy is needed for hepatitis B virus(HBV) infection resolvers with high titer of hepatitis B surface antibody(anti-HBs) receiving rituximab treatment.
Aim: To emphasize the role of antibiotics in acute pancreatitis as prophylactic and therapeutic benefits. Case Report: A 32-year-old obese male was admitted with acute abdomen in the ...