SITE-SPECIFIC

作品数：120被引量：357H指数：8
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相关作者：程涵王勇博薛宇朱文远李新新更多>>
相关机构：华中科技大学北京大学广东省人民医院(广东省医学科学院)中国科学院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家科技支撑计划更多>>
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  • 期刊=Chemical Research in Chinese Universitiesx
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Quantitative and Site-specific Analysis of Adenosine-to-inosine RNA Editing by Ligation-assisted qPCR
《Chemical Research in Chinese Universities》2025年第2期288-295,共8页TAO Wanbing GU Shuyi XIONG Jun YUAN Bifeng 
supported by the National Key R&D Program of China(No.2022YFC3400700);the National Natural Science Foundation of China(Nos.22074110,22277093,22207090);the Key Research and Development Project of Hubei Province,China(No.2023BCB094);the Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University,China(Nos.ZNJC202208,ZLJC2022001).
RNA molecules undergo a variety of modifications,including inosine modification,also called adenosine-to-inosine(A-to-I)RNA editing,which is prevalent across all domains of life.To unravel the roles of A-to-I RNA edit...
关键词：A-to-I RNA editing INOSINE RNA modification Quantification Site-specific detection 
Site-specific PEGylation of Human Growth Hormone by Mutated Sortase A被引量：1
《Chemical Research in Chinese Universities》2018年第3期428-433,共6页SHI Hui SHI Qingyang James T. OSWALD GAO Ying LI Leijiao LI Yunhui 
Supported by the Projects of Science ＆ Technology of Jilin Province, China（No.20150204030YY）, the Project of the Research and Development of Industrial Technology of Jilin Province, China（No.2015Y058） and the National Natural Science Foundation of China（No. 51402286 ）.
Human growth hormone（hGH）, a classic therapeutic protein, which promotes growth and wound healing, is released from the pituitary gland. As a protein drug, its short half-life is its main barrier to therapeutic effi...
关键词：Human growth hormone PEGYLATION Site specific modification 
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