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INOSINE: 作品数：40被引量：73H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：龚薇薇张红张礼和张亮仁杨振军更多>>; 相关机构：青岛大学东北财经大学北京大学更多>>; 相关期刊：《Journal of Pharmaceutical Analysis》《Chinese Herbal Medicines》《Journal of Animal Science and Biotechnology》《Chinese Journal of Natural Medicines》更多>>; 相关基金：国家自然科学基金更多>>

CAR-T overdrive:harnessing inosine for metabolic rewiring and stemness induction: 《Signal Transduction and Targeted Therapy》2024年第6期2347-2348,共2页MartíFarrera-Sal Michael Schmueck-Henneresse; a grant(CONAN,16GW0328K)provided by the Federal Ministry of Education and Research(BMBF).; In a recent Cancer Cell publication,Klysz et al.investigated the impact of inosine(INO),a catabolic product of adenosine(Ado),on Chimeric Antigen Receptor(CAR)T-cell function,stemness,and exhaustion.They provided insi...; 关键词：programming. CAR ADO

Sequencing methods and functional decoding of mRNA modifications被引量：1: 《Fundamental Research》2023年第5期738-748,共11页Kai Li Jinying Peng Chengqi Yi; the Ministry of Science and Technology of China(2019YFA0110902,2019YFA0802201)。; More than 160 types of post-transcriptional RNA modifications have been reported;there is substantial variation in modification type,abundance,site,and function across species,tissues,and RNA type.The recent developme...; 关键词：RNA modification N6 2′-O-dimethyladenosine(m6Am) N1-methyladenosine(m1A) 5-Methylcytosine(m5C) N6-methyladenosine(m6A) Pseudouridine(Ψ) Inosine(I)

Sensitive determination of inosine RNA modification in single cell by chemical derivatization coupled with mass spectrometry analysis被引量：1: 《Chinese Chemical Letters》2023年第10期98-101,共4页Wan-Bing Tao Neng-Bin Xie Qing-Yun Cheng Yu-Qi Feng Bi-Feng Yuan; supported by the National Key R&D Program of China(Nos.2022YFA0806600,2022YFC3400700);the National Natural Science Foundation of China(Nos.22277093,22074110,21721005).; Inosine is a vital RNA modification across three kingdoms of life.It has been demonstrated that inosine plays important roles in modulation of the fate of RNAs.In the current study,we developed a highly sensitive meth...; 关键词：INOSINE RNA modification CMCT DERIVATIZATION Mass spectrometry Single cell

Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia被引量：2: 《Food Science and Human Wellness》2023年第4期1379-1390,共12页Hongyuan Zhao Xiaoyu Chen Fanqiang Meng Libang Zhou Xinyi Pang Zhaoxin Lu Yingjian Lu; the National Natural Science Foundation of China(32072182).; Hyperuricemia is a critical threat to human health,and a high inosine diet can increase the prevalence of it.Lacticaseibacillus rhamnosus Fmb14 was isolated from traditional fermented Chinese yogurt,and its inosine de...; 关键词：Lacticaseibacillus rhamnosus Fmb14 HYPERURICEMIA Inosine degradation Uric acid metabolism

Inosine:A broad-spectrum anti-inflammatory against SARS-CoV-2 infection-induced acute lung injury via suppressing TBK1 phosphorylation: 《Journal of Pharmaceutical Analysis》2023年第1期11-23,共13页Ningning Wang Entao Li Huifang Deng Lanxin Yue Lei Zhou Rina Su Baokun He Chengcai Lai Gaofu Li Yuwei Gao Wei Zhou Yue Gao; from the Young Elite Scientists Sponsorship Program by CAST(Grant No.:2021-QNRC1-03);the National Key Research and Development Program of China(Grant No.:2020YFC0845400).; Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-induced cytokine storms constitute the primary cause of coronavirus disease 19(COVID-19)progression,severity,criticality,and death.Glucocorticoid and anti-cy...; 关键词：CYTOKINE stormInterleukin 6 (IL-6)InosineSARS-CoV-2TANK-binding kinase 1 (TBK1)

6-Thioguanine incorporates into RNA and induces adenosine-to-inosine editing in acute lymphoblastic leukemia cells被引量：1: 《Chinese Chemical Letters》2023年第1期539-543,共5页Xue-Jiao You Lin Li Tong-Tong Ji Neng-Bin Xie Bi-Feng Yuan Yu-Qi Feng; supported by the National Natural Science Foundation of China(Nos.22074110,21635006,21721005)。; 6-Thioguanine(6TG)is a widely used chemotherapeutic agent for the treatment of a variety of human diseases including acute lymphoblastic leukemia.After entry into cells,6TG is metabolically converted into 6-thioguanos...; 关键词：6-THIOGUANINE RNA modification INOSINE LEUKEMIA Mass spectrometry

Fire up the pyre:inosine thermogenic signaling for obesity therapy: 《Signal Transduction and Targeted Therapy》2022年第12期4255-4256,共2页Nienke Willemsen Stefan Kotschi Alexander Bartelt; S.K.was supported by the LMU Medical Faculty(FöFoLe);A.B.was supported by DFG and ERC grants.; In a recent study published in Nature,Niemann et al.may have discovered a metabolite signaling pathway that could pave the way to new weight loss drugs1(Fig.1).Obesity and its comorbidities are a major threat to publi...; 关键词：SINE WEIGHT DRUGS

Development of an eco-friendly and fast HPLC method for quantitative analysis of four nucleosides in Cordyceps and related products被引量：2: 《Chinese Journal of Natural Medicines》2021年第12期954-960,共7页QIAN Zheng-Ming WU Zi HUANG Qi WANG Chuan-Xi TAN Guo-Yin LI Wen-Jia SUN Wan-Yang LV Gen-Pin GAO Hao; supported by the National Natural Science Foundation of China (Nos.81925037, 82073976, and 31700013);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (No.2017BT01Y036);Guangdong Natural Science Funds for Distinguished Young Scholar(No.2021B1515020065);the Young Elite Scientists Sponsorship Program by the China Association of Chinese Medicine (No.QNRC2-B06);the Dongguan Academician Workstation Project (No.DGYSZ-2018-03)。; An eco-friendly and fast HPLC method was developed for the determination of adenosine, inosine, guanosine and uridine in Cordyceps and related products(fermented mycelia of Hirsutella sinensis and Paecilomyces hepiali...; 关键词：ADENOSINE INOSINE GUANOSINE URIDINE CORDYCEPS

Inosine: a novel treatment for sciatic nerve injury: 《Neural Regeneration Research》2021年第1期127-128,共2页Fellipe Soares dos Santos Cardoso Ana Maria Blanco Martinez Fernanda Martins de Almeida; Trauma to the peripheral nervous system often results in loss of motor and sensory functions of the affected area of the body,leading to a series of functional impairments(Allodi et al.,2012).Injuries to peripheral ne...; 关键词：al. DEGENERATION alterations

Inosine: novel microbiota-derived immunostimulatory metabolite被引量：5: 《Cell Research》2020年第11期942-943,共2页Guido Kroemer Laurence Zitvogel; In a recent paper published in Science,Mager et al.identify inosine as a metabolite produced by Bifidobacterium pseudolongum that improves the efficacy of anticancer immunotherapy in mice.Inosine produced in the gut r...; 关键词：EXPANDING INOSINE SINE

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