EPIMER

作品数:13被引量:9H指数:2
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相关领域:理学更多>>
相关作者:申大卫李中军孟祥豹田瑄钟鸣更多>>
相关机构:北京大学韶关大学兰州大学更多>>
相关期刊:《Advances in Bioscience and Biotechnology》《分析测试学报》《Chemical Research in Chinese Universities》《Science Bulletin》更多>>
相关基金:国家自然科学基金更多>>
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Picropodophyllotoxin: A Natural Epimer Targeting STAT3 Phosphorylation and ROS-Mediated Apoptosis in Oral Squamous Cell Carcinoma Cells
《BIOCELL》2025年第4期647-663,共17页Jung-ⅡChae Ji-Hye Seo Goo Yoon Young-Joo Jeon Woo-Keun Kim 
supported by the Korea Institute of Toxicology(KIT)Research Program[No.2710008763(KK-2401-01)];the Korea Environmental Industry&Technology Institute(KEITI)through the Core Technology Development Project for Environmental Diseases Prevention and Management[No.2480000072(RS-2021-KE001705)]。
Background:Picropodophllotoxin(PPT),a principal component of Podophyllum hexandrum root,demonstrates various beneficial biological activities in multiple cancer types,including antitumor and antiproliferative properti...
关键词:Picropodophyllotoxin STAT3 ROS oral squamous cell carcinoma APOPTOSIS 
A Review: Manufacturing, and Properties of the D-Fructose Epimer D-Allulose (D-Psicose)
《Advances in Bioscience and Biotechnology》2024年第9期522-542,共21页Osama O. Ibrahim 
D-allulose, also known by the name D-psicose or just allulose, is a rare keto-sugar epimer of D-fructose in the third carbon (C3), and naturally occurs in small quantity in fruits such as grapes and figs. It is low ca...
关键词:D-Allulose D-Ketose 3-Epimerase (DKEase) D-Tagatose 3-Epimerase (DTEase) D-Allulose 3-Epimerase (DAEase) D-Psicose 3-Epimerase (DPEase) 
Separation and simultaneous quantitation of PGF2α and its epimer 8-iso-PGF2α using modifier-assisted differential mobility spectrometry tandem mass spectrometry被引量:3
《Acta Pharmaceutica Sinica B》2018年第2期228-234,共7页Chunsu Liang Hui Sun Xiangjun Meng Lei Yina J.Paul Fawcett Huaidong Yu Ting Liu Jingkai Gu 
supported by the National Natural Science Foundation of China(Grant Nos.81430087 and 81673396)
Because many therapeutic agents are contaminated by epimeric impurities or form epimers as a result of metabolism, analytical tools capable of determining epimers are increasingly in demand. This article is a proof-of...
关键词:Differential mobility spectrometry Mass spectrometry EPIMER PGF2Α 8-ISO-PGF2Α 
Synthesis of 2-deoxy-2-chloro-1-amino sugars and evaluation of their cytotoxicity against cancer cells
《Journal of Chinese Pharmaceutical Sciences》2013年第2期144-147,共4页钟鸣 崔希凯 孟祥豹 李中军 
National Natural Science Foundation of China(NSFC,Grant No.21072017)
Using the potent anticancer agent 2-deoxy-2-chloro-1-amino sugar as a lead compound, its analogs were prepared in 6 steps starting from D-glucal. The key step was the synthesis of 2-chloro-1-acetamido sugars using (C...
关键词:2-Deoxy-2-chloro-1-amino sugars Cytotoxic activity Epimer 
Study of electrospray ionization tandem mass spectrometry of the benzofuranone compounds被引量:2
《Chinese Chemical Letters》2008年第3期324-328,共5页Zhan Qi Niu Yu Min Sun Feng Niu Jian Han Da Wei Chen 
A detailed analysis of benzofuranone compounds under multiple tandem mass spectrometry (ESI-MS^n) conditions is reported. Element composition data of the fragment ions were obtained with the aid of comparison of the...
关键词:ESI-MS^n Benzofuranones Epimer: cis-trans-Isomer 
鬼臼及其羧酸酯类化合物2位立体异构体的EIMS质谱研究
《分析测试学报》2007年第z1期109-112,共4页申大卫 田瑄 
Podophyllotoxin,picropodophyllotoxin and their eight esters were studied using EI MS.The 2-epimers of podophyllotoxin and its esters can be identified by calculating the rate of relative abundance of m/z 168,396 to mo...
关键词:2-epimer of podophyllotoxin Relative abundance EI MS 
Highly Oxygenated Monoterpenes from Eupatorium fortunei
《Chinese Chemical Letters》2005年第9期1217-1219,共3页Hal Xia JIANG Kun GAO 
This work was supported by the NNSFC(No.20372029 and No.20021001-QT Program);by the Key Project of Chinese Ministry of Education(No.104178).
A pair of epimers of highly-oxygenated monoterpenes were isolated from the traditional Chinese medicine Eupatorium fortunei. Their structures were elucidated on the basis of the spectral analysis as (1R*, 2S*, 3R*...
关键词:Eupatorium fortunei traditional Chinese medicine EPIMER highly-oxygenated monoterpenes 
Study on the Total Synthesis of Et 743 and its Analogues: Synthesis of a Tricyclic Intermediate and its 11-Epimer被引量:1
《Chinese Chemical Letters》2003年第10期996-998,共3页Ye Feng TANG, Zhan Zhu LIU, Shi Zhi CHENInstitute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union MedicalCollege, Beijing 100050 
The tricyclic compound 1, a key intermediate of the pentacyclic core of Et 743 and its analogues, was synthesized. Its 11-epimer was found as the product of racemization when BOP was used as the coupling agent, but no...
关键词:Et 743 tricyclic compound synthesis stereochemistry. 
Diastereoselective Syntheses of (+)-α-Cyperone and Its C-10 Epimer
《Chemical Research in Chinese Universities》1998年第3期126-128,共3页ZOU Ning CHENG Dong liang PAN Xin fu CHEN Yao zu 
Introduction(+)-α-Cyperone(1)and(-)-α-10-epicyperone(2)arewidelyusedaschiraltemplatesforthesynthesisofothers...
关键词:(+)-T-Cyperone (-)  -T-10-Epicyperone Diastereoselective synthesis 
A total synthesis of (+)-preussin and its 5-epimer被引量:1
《Chinese Journal of Chemistry》1998年第5期458-467,共10页董汉清 林国强 
Project supported by the National Natural Science Foundation of China
(+)-Preussin (1) and its 5-epimer were synthesized from the divinylcarbinol (3) with Sharpless asymmetric epoxidation of 3 and the oxidative cyclization of 9 with PDC as the key steps.
关键词:(+)-Preussin and its 5-epimer divinylcarbinol Sharpless asymmetric epoxidation oxidative cyclization 
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