the National Natural Science Foundation of China,No.81960504;the“Xingdian Talents”Support Project of Yunnan Province,No.RLQB20200002;the Medical Discipline Reserve Talents of Yunnan Province,No.H-2018015;the Applied Basic Research Projects-Union Foundation of Kunming Medical University,No.2017FE467(-132);the Talent Introduction Project of Hubei Polytechnic University,No.21xjz34R。
BACKGROUND Aberrant methylation is common during the initiation and progression of colorectal cancer(CRC),and detecting these changes that occur during early adenoma(ADE)formation and CRC progression has clinical valu...
Despite considerable advances in our understanding of cancer biology, early diagnosis of colorectal cancer remains elusive. Based on the adenoma-carcinoma sequence, cancer develops through the progressive accumulation...