We thank Drs J Zhao, DS Li, L Xiao (Chinese Academy of Sciences, China), Drs B Leo and H Wang (Agilent Technologies, USA) for helpful discussions and technical assistance, and Drs HK Mei and Y Qiu (GlaxoSmithKline, UK) for the DAVID analysis. This research was supported by the Ministry of Science and Technology (2005CB522406, 2006CB943900, 2007CB947904, 2007CB947100, 2009CB941100, and 2007CB948000), National Natural Science Foundation of China (30621091, 30625014, 30623003, and 90713047), Shanghai Municipal Commission for Science and Technology (07PJ14099, 06ZR14098, and 06DZ22032), and the Chinese Academy of Sciences (KSCX2-YW-R-56 and 2007KIP204).
Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their overexpression can induce pluripotency in both mouse and human somatic cells, indicating that these factors...
the National Basic Research Program of China (No 2005CB522404 and 2006CB910506);the Program for Changjiang Scholars and Innovative Research Team (PCSIRT) in Universities (No IRT0519);the National Natural Science Founda-tion of China (No 30771232 and 30671184)
Mesenchymal stem cells (MSCs) of nonembryonic origins possess the proliferation and multi-lineage differentiation potentials. It has been established that epigenetic mechanisms could be critical for determining the ...