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BOX: 作品数：1241被引量：2882H指数：18; 导出分析报告; 相关领域：医药卫生轻工技术与工程更多>>; 相关作者：周惠屈良鹄何凤田赵建军张艳更多>>; 相关机构：中国科学院苏州浪潮智能科技有限公司辽宁优迅科技有限公司中山大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家科技重大专项更多>>

Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-inducedβ-cell dedifferentiation: 《World Journal of Diabetes》2025年第5期216-233,共18页Li-Kun Wang Chu-Chu Kong Ting-Yan Yu Hui-Song Sun Lu Yang Ying Sun Ming-Yu Li Wei Wang; Supported by the Natural Science Foundation of China,No.81471081;the Natural Science Foundation of Fujian Province,No.2023D009;the Natural Science Foundation of Xiamen City,No.3502Z202373104 and No.3502Z20227162;Scientific Research Foundation for Advanced Talents,Xiang’an Hospital of Xiamen University,No.PM201809170005。; BACKGROUND Type 2 diabetes mellitus is characterized by pancreaticβ-cell dysfunction and insulin resistance.Studies have suggested thatβ-cell dedifferentiation is one of the pathogeneses ofβ-cell dysfunction,but th...; 关键词：β-cell dedifferentiation High glucose and palmitic acid Forkhead box O1 RNA-sequencing Endoplasmic reticulum stress

Analytical solution of overlying pressure for shallowly buried underwater box tunnel:A case study of box jacking in Suzhou,China: 《Journal of Rock Mechanics and Geotechnical Engineering》2025年第4期2328-2343,共16页Cheng Cheng Pengjiao Jia Pengpeng Ni Peixin Shi Qiao Xiang Yang Chen; supported by the Natural Science Foundation of Jiangsu Province of China (Grant Nos.BK20230500 and BK20210721);the Young Talent Fund of Association for Science and Technology in Shaanxi,China (Grant No.20240722).; Accurately predicting the overlying pressure is crucial for determining an appropriate cover depth of underwater box tunnels to avoid the uplifting failure.Based on the project of box jacking crossing the Beijing-Hang...; 关键词：Underwater box tunnel Overlying pressure Minimum cover depth Anti-floating behavior

Investigation of high-mobility group box 1 variants with lymph node status and colorectal cancer risk: 《World Journal of Gastrointestinal Oncology》2025年第4期67-80,共14页Xin Liu Sheng Zhang Hao Qiu Zhi-Qiang Xie Wei-Feng Tang Yu Chen Xi Wei; Supported by the Major Project of Changzhou Science and Technology Bureau,No.CJ20220255.; BACKGROUND Accumulating studies indicated that maintain nuclei homeostasis was deemed to the protective factors for the occurrence of cancer.Thus,high-mobility group box 1(HMGB1)might influence the risk and poorer pro...; 关键词：High-mobility group box 1 Colorectal cancer POLYMORPHISM Immune Lymph nodes metastasis

Interferon-αstimulates DExH-box helicase 58 to prevent hepatocyte ferroptosis: 《Military Medical Research》2025年第2期184-203,共20页Kai-Wei Jia Ren-Qi Yao Yi-Wen Fan Ding-Ji Zhang Ye Zhou Min-Jun Wang Li-Yuan Zhang Yue Dong Zhi-Xuan Li Su-Yuan Wang Mu Wang Yun-Hui Li Lu-Xin Zhang Ting Lei Liang-Chen Gui Shan Lu Ying-Yun Yang Si-Xian Wang Yi-Zhi Yu Yong-Ming Yao Jin Hou; National Key Research and Development Program of China(2023YFC2505900);National Natural Science Foundation of China(92269204,82171755,92369106,82171749,82171811,82073184);Military Outstanding Youth Program(2020QN06119,01-SWK JYCJJ07,23SWAQ53);Program of Leading Talents in Shanghai,and Shanghai Shuguang Program(20SG39)。; Background Liver ischemia/reperfusion(I/R)injury is usually caused by hepatic inflow occlusion during liver surgery,and is frequently observed during war wounds and trauma.Hepatocyte ferroptosis plays a critical role ...; 关键词：Ischemia/reperfusion(I/R) DExH-box helicase 58(DHX58) Glutathione peroxidase 4(GPX4) m6A modification YT521-B homology domain containing 2(YTHDC2)

MediServe:An IoT-Enhanced Deep Learning Framework for Personalized Medication Management for Elderly Care: 《Computers, Materials & Continua》2025年第4期935-976,共42页Smita Kapse Ganesh Yenurkar Vincent Omollo Nyangaresi Gunjan Balpande Shravani Kale Manthan Jadhav Sahil Lawankar Vikrant Jaunjale; In today’s fast-paced world,many elderly individuals struggle to adhere to their medication schedules,especially those with memory-related conditions like Alzheimer’s disease,leading to serious health risks,hospital...; 关键词：MediServe MEDICATION health risks smart medication box

DNA methyltransferase 1/miR-342-3p/Forkhead box M1 signaling axis promotes self-renewal in cervical cancer stem-like cells in vitro and nude mice models: 《World Journal of Stem Cells》2025年第3期44-64,共21页Xiao-Zheng Cao Yao-Feng Zhang Yu-Wei Song Lei Yuan Hui-Li Tang Jin-Yuan Li Ye-Bei Qiu Jia-Zhi Lin Ying-Xia Ning Xiao-Yu Wang Yong Xu Shao-Qiang Lin; Supported by Guangzhou Basic and Applied Basic Research Foundation,No.202201010121;Medical Joint Fund of Jinan University,No.YXZY2024014 and No.YXJC2022001;Hospital Achievement Transformation and Cultivation Project,No.ZH201911;the Key Discipline Project of Guangdong Province,No.2019-GDXK-0016;and the Medical Science and Technology Research Foundation of Guangdong Province,No.B2021145.; BACKGROUND Cervical cancer(CC)stem cell-like cells(CCSLCs),defined by the capacity of differentiation and self-renewal and proliferation,play a significant role in the progression of CC.However,the molecular mechanism...; 关键词：DNA methyltransferase 1 Cancer stem cell Cervical cancer MiR-342-3p Forkhead box M1

谷物联合收获机清选装置参数监控与优化试验: 《中国农机化学报》2025年第3期208-215,共8页陈新奇耿令新庞靖黄胜操王升升林毅; 国家自然科学基金项目(52005163);河南省科技攻关项目(232102111120)。; 为研究谷物联合收获机在不同喂入量下的最优参数组合,设计谷物联合收获机清选装置多参数监控系统。在此系统基础上,开展清选装置参数优化试验,研究清选装置参数对含杂率、损失率的影响规律,得到含杂率、损失率回归模型;取含杂率权重为0...; 关键词：谷物联合收获机清选装置作业参数监控喂入量 Plackett—Burman试验 Box—Behnken试验

PAK5与p53竞争结合DDX5促进乳腺癌细胞的增殖: 《现代肿瘤医学》2025年第5期749-755,共7页蔡伊航王乐严赵鑫李洋; 辽宁省教育厅青年科学家项目(编号:LJ212410159117);辽宁省沈阳市科技局2023年助力中国医科大学高质量发展专项(编号:23-506-3-01-34)。; 目的:探讨p21活化激酶-5(p21-activated kinase 5,PAK5)通过磷酸化修饰对DDX5与p53结合的影响和可能机制。方法:为了探究PAK5对DDX5与p53结合的影响,在过表达PAK5的乳腺癌细胞中,采用Co-IP验证DDX5与p53结合能力的变化,并在细胞外利用GS...; 关键词：磷酸化竞争性结合 p21活化蛋白5(PAK5) DEAD box RNA解旋酶5(DDX5)

凌华EMP-520系列:4K多屏+工业级BOX PC,解锁边缘视觉与物联新战力: 《自动化博览》2025年第2期9-9,共1页; 凌华智能推出全新EMP-520系列工业级超紧凑BOX PC,硬核搭载第14代英特尔■酷睿^(TM)Ultra处理器,军工级宽温设计,工业级长时间系统运作,实现四路4K独立输出+双千兆物联组网。从智能制造产线到户外数字标牌,这台「工业小钢炮」用体积缩小...; 关键词：第14代英特尔酷睿凌华EMP-520系列

Boom Box 3遥爆系统与电子雷管在G3i仪器中的应用: 《物探装备》2025年第1期49-51,共3页李伟利蒋福罡周成宽邢永强米辉; 本文详细介绍了Boom Box 3遥爆系统,MAXAM电子雷管与G3i仪器联机使用时编码器的改进与取得的市场成果;Boom Box 3编码器与G3i仪器硬件接口的连接方法和注意事项;Boom Box 3编码器译码器软件的关键参数设置及含义;G3i仪器的软件的关键参...; 关键词：Boom Box3 G3i仪器电子雷管编译码器

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