National Key Research and Development Program of China(2023YFC2505900);National Natural Science Foundation of China(92269204,82171755,92369106,82171749,82171811,82073184);Military Outstanding Youth Program(2020QN06119,01-SWK JYCJJ07,23SWAQ53);Program of Leading Talents in Shanghai,and Shanghai Shuguang Program(20SG39)。
Background Liver ischemia/reperfusion(I/R)injury is usually caused by hepatic inflow occlusion during liver surgery,and is frequently observed during war wounds and trauma.Hepatocyte ferroptosis plays a critical role ...
Supported by Guangzhou Basic and Applied Basic Research Foundation,No.202201010121;Medical Joint Fund of Jinan University,No.YXZY2024014 and No.YXJC2022001;Hospital Achievement Transformation and Cultivation Project,No.ZH201911;the Key Discipline Project of Guangdong Province,No.2019-GDXK-0016;and the Medical Science and Technology Research Foundation of Guangdong Province,No.B2021145.
BACKGROUND Cervical cancer(CC)stem cell-like cells(CCSLCs),defined by the capacity of differentiation and self-renewal and proliferation,play a significant role in the progression of CC.However,the molecular mechanism...
The funding for this publication was provided by Johannes Kepler University(JKU),Linz.Special thanks to Prof.Zongmin DENG from Beihang University for his invaluable guidance,insightful feedback,and constructive criticism,which greatly enhanced the quality of this manuscript.We extend our heartfelt gratitude to the PARSIFAL team for providing the supporting materials,which inspired this study.
The optimization of wings typically relies on computationally intensive high-fidelity simulations,which restrict the quick exploration of design spaces.To address this problem,this paper introduces a methodology dedic...
supported by Guangxi Natural Science Foundation(No.2023GXNSFDA026047);Guangxi Science and Technology Project(No.FANGKE ZY20221502);the National Natural Science Foundation of China(No.82160948);the Advanced Innovation Teams and Xinghu Scholars Program of Guangxi Medical University。
Xiaoaiping(XAP)Injection demonstrates the anti-prostate cancer(PCa)effects,yet the underlying mechanism remains unclear.This study aims to investigate the impact of XAP on PCa and elucidate its mechanism of action.PCa...
supported by a grant of the M.D.-Ph.D./Medical Scientist Training Program through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(to HK);supported by National Research Foundation of Korea(NRF)grants funded by the Korean government(MSIT;Ministry of Science and ICT)(NRF2019R1A5A2026045 and NRF-2021R1F1A1061819);a grant from the Korean Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(HR21C1003);New Faculty Research Fund of Ajou University School of Medicine(to JYC)。
High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the ex...
supported by the National Key R&D Program of China(No.2022YFB3404204);the National Natural Science Foundation of China(No.U2241232);the Foundation of National Key Laboratory for Precision Hot Processing of Metals,China(No.6142909230203).
To form complex box-shape parts with large wall-thickness difference,a directly thixoforged technology of 2A14 alloy with low-cost and short-process was proposed and verified.The results showed that complex components...