L-LEUCINE

作品数：22被引量：14H指数：2
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相关领域：理学医药卫生更多>>
相关作者：马超孙久荣刘梅刘炎钱晓伟更多>>
相关机构：南通大学北京大学精晶药业股份有限公司厦门元尊生物工程有限公司更多>>
相关期刊：《Journal of Animal Science and Biotechnology》《中国高新科技》《Chinese Journal of Polymer Science》《Neural Regeneration Research》更多>>
相关基金：国家自然科学基金广东省自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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Retraction notice to“L-Leucine stimulates glutamate dehydrogenase activity and Glutamate synthesis by regulating mTORC1/SIRT4 pathway in pig liver”[Animal Nutrition 4(2018)329e338]
《Animal Nutrition》2024年第4期488-488,共1页Tongxin Wang Weilei Yao Qiongyu He Yafei Shao Ruilong Zheng Feiruo Huang 
This article has been retracted:please see Elsevier Policy on Article Withdrawal(https://www.elsevier.com/about/policies/articlewithdrawal).This article has been retracted at the request of the Editors-in-Chief,follow...
关键词：PLEASE ELSEVIER ANIMAL 
Modification of the substrate specificity of leucine dehydrogenase by site‑directed mutagenesis based on biocomputing strategies
《Systems Microbiology and Biomanufacturing》2023年第2期384-392,共9页Jiapeng Lu Zengyu Wang Yingying Jiang Zhoutong Sun Wei Luo 
supported by the Key Technology Research Plan Project of the Inner Mongolia Autonomous Region(2019GG302);the Program of the Key Laboratory of Carbohydrate Chemistry&Biotechnology,Ministry of Education,China(KLCCB-KF202103).
Synthesis of chiral amines by amine dehydrogenase has the advantages of environmental friendliness,high stereoselectivity,and mild reaction conditions.However,amine dehydrogenase has low catalytic activity,which great...
关键词：Amine dehydrogenase L-leucine dehydrogenase Semi-rational design Protein engineering Substrate binding pocket 
Determination of Atomic Fractions of Isotopes Carbon-13 and Nitrogen-15 Directly in Glicine, L-Leucine, Isoleucine and Alanine
《American Journal of Analytical Chemistry》2023年第5期229-237,共9页Levani Eliashvili Lamzira Parulava Vakhtang Betlemidze 
Using compounds modified by the isotopes carbon-13 and nitrogen-15 helps conduct research in various fields of science, such as medicine, pharmacology, pharmacokinetics, metabolism, agriculture, and others. In the cas...
关键词：Mass Spectrometer Mass Spectrum Fragmentary Ion Ionization Mass-to-Charge Ratio Intensity of Ionic Current Carbon-13 Nitrogen-15 Atomic Fraction Isotope-Modified 
N-acetyl-L-leucine: a promising treatment option for traumatic brain injury
《Neural Regeneration Research》2022年第9期1957-1958,共2页Chinmoy Sarkar Marta M.Lipinski 
supported by IntraBio and NIH funding(R01NS091218 and R01NS091218)to MML.
Traumatic brain injury(TBI)is a mechanical injury to the brain,which can be sustained due to falls,accidents,contact sports or in combat situation.It is a serious health problem-affecting people of all ages worldwide....
关键词：SUSTAINED TRAUMATIC injury 
L-leucine stimulates glutamate dehydrogenase activity and glutamate synthesis by regulating mTORC1/SIRT4 pathway in pig liver被引量：1
《Animal Nutrition》2018年第3期329-338,共10页Tongxin Wang Weilei Yao Qiongyu He Yafei Shao Ruilong Zheng Feiruo Huang 
the National Key Research and Development Program(Grant No.2016YFD0500506);the National Natural Science Foundation of China(Grant No.31572409);National Basic Research Program of China(Grant No.2013CB127304)provided the funds necessary for the conduction of this study
The liver is the most essential organ for the metabolism of ammonia, in where most of ammonia is removed by urea and glutamine synthesis. Regulated by leucine, glutamate dehydrogenase(GDH) catalyzes the reversible int...
关键词：Glutamate dehydrogenase activity Glutamate synthesis L-LEUCINE mTORC1/SIRT4 pathway Pig liver 
Microwave-Assisted Facile and Rapid Esterification of Amino Acids I: Esterification of L-Leucine from Batch to Flow Processes and Scale-Up
《Natural Science》2017年第4期110-122,共13页Ritsuko Nagahata Takashi Nakamura Yukie Mori Kazuhiko Takeuchi 
We herein report our studies into the effects of microwave irradiation on the solvent-free esterification of L-leucine with alcohols. In the absence of solvent, microwave irradiation accelerated the reaction compared ...
关键词：MICROWAVE-ASSISTED ESTERIFICATION Microwave Flow Reactor Dielectric Properties Amino Acid ESTER L-LEUCINE 
Cu(II) Complex of L-Leucine Favor a Different Type of Crystal Structure from Cu(II)-L-Val and Cu(II)-L-Ile
《Advances in Chemical Engineering and Science》2016年第1期62-66,共5页Masaaki Yokota Shingo Kikuchi Jun Sen Toshimichi Kamei Norihito Doki 
Crystallization behavior of Cu(II) complexes of branched chain amino acids (BCAAs) has been studied. Mixing of Cu(II) and L-leucine in solution caused immediate precipitation of Cu(II)-L-Leu complex, while no precipit...
关键词：CRYSTALLIZATION Crystal Structure Copper Complex Branched Chain Amino Acid 
Self-assembly and pH-Responsive Properties of Poly(L-glutamic acid-r-Lleucine) and Poly(L-glutamic acid-r-L-leucine)-b-Polysarcosine被引量：1
《Chinese Journal of Polymer Science》2015年第8期1186-1195,共10页Ce Tian 凌君 You-qing Shen 
financially supported by the National Natural Science Foundation of China(Nos.21174122 and 51390481)
Polypeptides and polypeptoids were widely used as biomedical materials because of their good biocompatibility. In this work we reported a series of pH-responsive copolypeptides and polypeptide-polypeptoid block copoly...
关键词：α-Amino acid NCA Random/block copolypeptide PH-RESPONSIVE Hydrophilicity-hydrophobicity transition. 
Modifications of L-Glutamine and L-Leucine Transport in Proliferating Lymphocytes
《Journal of Biosciences and Medicines》2015年第3期104-109,共6页Francisco Sanchez Jose Luis Gil Macarena Perán 
Lymphocytes respond to mitogens that stimulate proliferation by increasing theirs metabolic activity. In this study we investigate L-Glutamine and L-Leucine uptake as markers of cell response to Concavalina A (ConcaA)...
关键词：Cell Membrane TRANSPORT LYMPHOCYTES L-GLUTAMINE L-LEUCINE MALIGNANCY Biomarkers 
Effects of “Bioactive” amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks被引量：4
《Journal of Animal Science and Biotechnology》2012年第4期199-206,共8页Songbo Wang Paul Khondowe Shengfeng Chen Jianjian Yu Gang Shu Xiaotong Zhu Lina Wang Ping Gao Qianyun Xi Yongliang Zhang Qingyan Jiang 
supported by National Key Project(2009CB941601);the Joint Funds of the National Natural Science Foundation of China(u0731004);National Natural Science Foundation of China(30871845,30901058 and 30972157);the Natural Science Foundation of Guangdong Province of China(9451064201003790 and 9151064201000056);the Special Fund for Agro-scientific Research in the Public Interest(201003011);Specialized Research Fund for the Doctoral Program of Higher Education of China(20094404120012)
Feed intake control is vital to ensuring optimal nutrition and achieving full potential for growth and development in poultry. The aim of the present study was to investigate the effects of L-leucine, L-glutamate, L-t...
关键词：Broiler chicks Feed intake HYPOTHALAMUS Intracerebroventricular （ICY） L-LEUCINE L-GLUTAMATE 
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