financially supported by the National Natural Science Foundation of China(Nos.52025102,52192682,and 52200057);the Jiangsu Funding Program for Excellent Postdoctoral Talent(China)(No.2022ZB35).
Class 1 integrons are vital mobile genetic elements involved in the environmental transmission of antibiotic resistance genes(ARGs).However,knowledge about the diversity and abundance of class 1 integrons and gene cas...
Acinetobacter baumannii is the main drug resistant bacteria in clinic at present, and its drug resistance is still rising rapidly. Integrons play an important role in bacterial acquisition of exogenous drug r...
supported by the National Natural Science Foundation of China(No.51678003)
The coastal area of the East China Sea has experienced rapid urbanization and industrialization in China since 1980 s, resulting in severe pollution of its environments.Antibiotic resistance genes(ARGs) are regarded a...
Objective: To investigate the frequency of integrase genes intI1, intI2 and intI3 of Escherichia coli strains, and their association with resistance to routinely used antibiotics. Methods: A total of 120 Escherichia c...
supported by the National Natural Science Foundation of China(No.51138006);the National Key Research on Water Environment Pollution Control in China(No.2012ZX07301-001)
The emergence and prevalence of antibiotic resistance genes(ARGs) and pathogens in the environment are serious global health concern. However, information about the occurrence of ARGs and pathogens in recreational wat...
Rivers can act as reservoirs of highly resistant strains and facilitate the dissemination of resistance, virulence and integron 1 genes. A cross-sectional study was carried out where 318 water samples were collected (...
Supported by the Fund of Hubei 2011 Cooperative Innovation Center(2011JH-2013CXTT01)
Objective The aim of our study is to investigate the prevalence of Carbapenem-resistant Klebsiella pneumoniae (CRKP) and the genetic characteristics of the class 1 integron in CRKP on multi-drug resistance. Methods...
funded by the National Natural Science Foundation of China(No.81000754 and No. 81471994);received a grant from the Key Laboratory for Laboratory Medicine of Jiangsu Province of China(No.XK201114)
Rapid dissemination of antibiotic resistance genes among bacterial isolates is an increasing problem in China. Integron, a conserved DNA sequence, which is carried on episomal genetic structures, plays a very importan...
Pseudomonas aeruginosa is one of the most important opportunistic human pathogens worldwide. High prevalence of Multi Drug Resistant P. aeruginosa (MDRPa) in Iran is a serious problem for antimicrobial therapy. Severa...
Extensive use of antibacterials in clinical practice has been associated with increasing frequency of multi-resistant E. coli strains. Genetic elements such as Class 1 integrons have an important role in resistance de...