Alzheimer Society UK.UK Dementia Research Institute(DRIEdi17/18MRC MC_PC_17113);British Heart Foundation(CS/15/5/31475);The Stroke Association.Mrs Gladys Row Fogo Charitable Trust(AD.ROW4.35D.FID3668413);Fondation Leducq Transatlantic Network of Excellence for the Study of Perivascular Spaces.Alzheimer’s Research UK.UK Medical Research Council.
Cerebral small vessel disease(cSVD)causes lacunar stroke(25%of ischaemic strokes),haemorrhage,dementia,physical frailty,or is‘covert’,but has no specific treatment.Uncertainties about the design of clinical trials i...
supported by the Shanxi Provincial Key Research and Development Project(202102130501004).
TAG-assisted peptide synthesis technology enables optimal conservation of Fmoc amino acid raw materials and chemical solvents while eliminating the need for intricate chromatographic purification processes.This work p...
the Medical and Health Science and Technology Program of Zhejiang Province(2019KY111);Foundation of Wenzhou City Science&Technology Bureau(Y2020037);EYE&ENT Hospital of Fudan University High-level Talents Program(2021318);Clinical Research Plan of SHDC(SHDC2020CR1043B)。
Background:To evaluate the precision of corneal higher-order aberrations measurements after small incision lenticule extraction(SMILE)using the Sirius Scheimpfug-Placido topographer(CSO,Italy).Methods:Seventy-fve eyes...
supported in part by the Foundation of Wenzhou City Science&Technology Bureau(Grant No.Y2020037);Medical and Health Science and Technology Program of Zhejiang Province(Grant No.2019KY111);Zhejiang Provincial&Ministry of Health Research Fund for Medical Sciences(Grant No.WKJ-ZJ-2134);Zhejiang Provincial High-level Talents Program(Grant No.2017-102).
Background:To compare the difference in central corneal thickness(CCT)measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer(Sirius,CSO,Italy)and ultrasound ...
support for the research,authorship,and/or publication of this article:This work is supported by British Heart Foundation(CS/15/5/31475);the Alzheimer’s Society(AS-PG 14-033);EU Horizon 2020 SVDs@Target(666881);MRC UK DRI,Fondation Leducq(16/05 CVD);NHS Research Scotland,The Stroke Association and Garfield-Weston Foundation,Chief Scientist Office(UC);National Institute of Health Research.PMB is Stroke Association Professor of Stroke Medicine and an Emeritus NIHR Senior Investigator.
Background Cerebral small vessel disease(SVD)causes lacunar strokes(25%of all ischaemic strokes),physical frailty and cognitive impairment and vascular and mixed dementia.There is no specific treatment to prevent prog...
Bath PM,Mhlanga I,Woodhouse LJ,et al.Cilostazol and isosorbide mononitrate for the prevention of progression of:baseline data and statistical analysis plan for the Lacunar Intervention Trial-2(LACI-2)(ISRCTN14911850)....
supported by the National Key Research and Development Program of China(2018YFA0900100);the National Natural Science Foundation of China(31670081).
Intracellular pH critically affects various biological processes,and an appropriate cytoplasmic pH is essential for ensuring bacterial growth.Glucose is the preferred carbon source for most heterotrophs;however,excess...
supported in part by the Foundation of Wenzhou City Science&Technology Bureau(Y2020037);Medical and Health Science and Technology Program of Zhejiang Province(2019KY111);Zhejiang Provincial&Ministry of Health Research Fund for Medical Sciences(WKJ-ZJ-2134);Zhejiang Provincial High-level Talents Program(2017–102).
Background:To compare the difference in central corneal thickness(CCT)measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer(Sirius,CSO,Italy)and ultrasound ...