CHEMOTHERAPEUTICS

作品数:25被引量:83H指数:5
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相关领域:医药卫生更多>>
相关作者:傅健文陈宏更多>>
相关机构:天津市长征医院天津医科大学总医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Research》《Journal of Hainan Medical University》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划上海市教育委员会重点学科基金国家教育部博士点基金更多>>
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  • 期刊=Cell Researchx
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Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells被引量:7
《Cell Research》2018年第5期544-555,共12页Chen Qi Xin Wang Zhirong Shen She Chen Hong Yu Noelle Williams Gelin Wang 
The commonly used antimitotic chemotherapeutic agents such as taxol and vinblastine arrest cell cycle progression by disrupting mitotic spindles, and cause cancer cells to undergo apoptosis through 'mitotic catastro...
关键词:APOPTOSIS 有丝分裂 死亡受体 房间 癌症 激活 TAXOL 代理人 
Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics被引量:22
《Cell Research》2015年第6期707-725,共19页Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim 
Receptor-interacting protein kinase-3 (RIP3 or RIPK3) is an essential part of the cellular machinery that executes "programmed" or "regulated" necrosis. Here we show that programmed necrosis is activated in resp...
关键词:RIP3 (RIPK3) MLKL programmed necrosis CHEMOTHERAPY hypomethylating agents 
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