PREDNISOLONE

作品数：48被引量：150H指数：6
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相关领域：医药卫生更多>>
相关作者：刘三康李章万付春梅孙毅之贺银凤更多>>
相关机构：四川大学中国检验检疫科学研究院内蒙古农业大学东北师范大学更多>>
相关期刊：《World Journal of Translational Medicine》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金更多>>
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Pharmacokinetic Evaluation of Chitosan-Succinyl-Prednisolone Conjugate Microparticles as a Colonic Delivery System: Comparison with Enteric-Coated Conjugate Microparticles
《Health》2014年第11期1286-1295,共10页Hiraku Onishi 
In the previous study, chitosan-succinyl-prednisolone conjugate microparticles (MP) were found to exhibit good efficacy and reduced toxicity nearly as well as their Eudragit L-coated microparticles (MP/EuL). This prop...
关键词：Chitosan-Succinyl-Prednisolone CONJUGATE Microparticle Enteric-Coating Pharmacokinetic Feature Gastrointestinal Behavior 2 4 6-Trinitrobenzenesulfonic Acid-Induced Ulcerative Colitis 
Synthesis and in vivo distribution of 2-deoxy-2-aminodiglucose-prednisolone conjugate(DPC)被引量：1
《Chinese Chemical Letters》2012年第5期557-560,共4页Yan Lin Xun Sun Tao Gong Zhi Rong Zhang 
supported by the National Science & Technology Major Project of China(No2009ZX09310-002)
In order to develop a novel kidney-targeted drug delivery system,a small molecular carrier（2-deoxy-2-aminodiglucose） was synthesized,and then the 2-deoxy-2-aminodiglucose-prednisolone conjugate（DPC） was synthesize...
关键词：SYNTHESIS 2-Deoxy-2-aminodiglucose PREDNISOLONE Tissue distribution 
Prednisolone succinate-glucosamine conjugate:Synthesis,characterization and in vitro cellular uptake by kidney cell lines被引量：4
《Chinese Chemical Letters》2012年第1期25-28,共4页Yan Lin Xun Sun Tao Gong Zhi Rong Zhang 
supported by the National Science & Technology Major Project of China(No.2009ZX09310- 002)
Prednisolone succinate-glucosamine（PSG） conjugate,a prodrug for prednisolone,was synthesized and confirmed by NMR and MS spectrum.The stabilities of the prodrug in PBS（pH 2.50,5.00,7.20,and 7.89） were studied.Cyto...
关键词：Glucosamine Prednisolone Prodrug Cytotoxicity Uptake 
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