GERMACRONE

作品数：4被引量：17H指数：2
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相关期刊：《Journal of Chinese Pharmaceutical Sciences》《Acta Biochimica et Biophysica Sinica》更多>>
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Germacrone ameliorates acute lung injury induced by intestinal ischemia-reperfusion by regulating macrophage M1 polarization and mitochondrial defects
《Acta Biochimica et Biophysica Sinica》2025年第2期261-273,共13页Yunguang Wang Xinxin He Hua Zhang Wei Hu 
supported by the grants from the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Hangzhou Health Science and Technology Plan-Major Project(No.Z20220026).
Intestinal ischemia-reperfusion(I/R)injury severely affects the lungs.Germacrone(Ger)possesses anti-inflammatory and antioxidant properties.However,it is unclear whether it protects the lungs from I/R injury.In this s...
关键词：lung injury GERMACRONE macrophage polarization mitochondrial function intestinal ischemia-reperfusion 
Integrated 16S rRNA sequencing and metabolomic analysis reveals the potential protective mechanism of Germacrone on diabetic nephropathy in mice
《Acta Biochimica et Biophysica Sinica》2024年第3期414-426,共13页Yunguang Wang Xinxin He Mengjiao Xue Huan Yu Qiang He Juan Jin 
This work was supported by the grants from the Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project(No.2022ZB273);the Huadong Medicine Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.LHDMY24H270002);the Zhejiang Provincial Medical and Health Technology Project(No.2023KY158);the Cultivation Program for Excellent Young Talents of Hangzhou First People’s Hospital(No.YQNYC202131);the Science and Technology Special Project of Hangzhou Biomedicine and Health Industry Development Support(No.2021WJCY253).
Diabetic nephropathy(DN)is a severe complication of diabetes and the leading cause of end-stage renal disease and death.Germacrone(Ger)possesses anti-inflammatory,antioxidant and anti-DN properties.However,it is uncle...
关键词：diabetic nephropathy GERMACRONE gut microbiota untargeted fecal metabolomics 16S rRNA sequencing 
Germacrone Induces Apoptosis in Human Hepatoma HepG2 Cells through Inhibition of the JAK2/STAT3 Signalling Pathway被引量：13
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2013年第3期339-345,共7页柳昀熠 郑倩 方斌 王维 马凤云 Sadia Roshan Amal Banafa 陈明洁 常俊丽 邓小敏 李克秀 杨广笑 何光源 
supported by grants from the National Major Project of the People's Republic of China (Nos. 2011ZX08002-004 and 2011ZX08010-004);the Wuhan Science and Technology Project (No. 201260523185);the International Scientific and Technological Cooperation Project of Ministry of Science and Technology of China (No. 2009DFB20290)
Summary： Previous studies have shown that STAT3 plays a vital role in the genesis and progression of cancer. In this study, we investigated the relationship between the JAK2/STAT3 signalling pathway and germacrone-in...
关键词：GERMACRONE JAK2/STAT3 APOPTOSIS HepG2 ceils 
High-Performance Liquid Chromatographic Method for Determination of Germacrone in Rat Plasma被引量：4
《Journal of Chinese Pharmaceutical Sciences》2004年第3期190-192,共3页HEHai-bing TANGXing CUIFu-de 
Aim A reliable high-performance liquid chromatographic (HPLC) method wasdeveloped for determination of germacrone in rat plasma. Methods The plasma samples were treatedwith acetonitrile and analyzed by HPLC with UV de...
关键词：high-performance liquid chromatography GERMACRONE volatile oil of rhizomacurcumae 
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