TOXINS

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Obituary:Prof.Yun Zhang(1963-2023)-A scientist focused on toxins and their underlying mechanisms to decipher human diseases
《Zoological Research》2024年第1期230-232,共3页Wenhui Lee Ren Lai 
Prof.Yun Zhang was born on 9 July 1963 in Kunming,Yunnan,China,during a tumultuous period which he often referenced.Throughout his life,he harbored a steadfast belief in using knowledge to unravel the mysteries of hum...
关键词：admitted harbor MECHANISMS 
Comparative analysis of diverse toxins from a new pharmaceutical centipede,Scolopendra mojiangica被引量：2
《Zoological Research》2020年第2期138-147,共10页Zi-Chao Liu Jin-Yang Liang Xin-Qiang Lan Tao Li Jia-Rui Zhang Fang Zhao Geng Li Pei-Yi Chen Yun Zhang Wen-Hui Lee Feng Zhao 
supported by grants from the Chinese National Natural Science Foundation(81860696,31560596,81373945,and 31360516);Yunnan Applied Basic Research Projects(2016FD076);Key Research Program of the Chinese Academy of Sciences(KJZD-EW-L03);"Yunling Scholar"Program,Yunnan Provincial Training Programs of Youth Leader in Academic and Technical Reserve Talent(2019HB058);Puer University(2017XJKT12&CXTD011)。
As the oldest venomous animals,centipedes use their venom as a weapon to attack prey and for protection.Centipede venom,which contains many bioactive and pharmacologically active compounds,has been used for centuries ...
关键词：CENTIPEDE TOXINS PHARMACEUTICAL USE Proteotranscriptomic analysis 
Receptor variability-driven evolution of snake toxins被引量：1
《Zoological Research》2018年第6期431-436,共6页Xian-Hong Ji Shang-Fei Zhang Bin Gao Shun-Yi Zhu 
supported by the National Natural Science Foundation of China(Grant No.31570773);State Key Laboratory of Integrated Management of Pest Insects and Rodents(Chinese IPM1707)
Three-finger toxins （TFTs） are well-recognized non- enzymatic venom proteins found in snakes. However, although TFTs exhibit accelerated evolution, the drivers of this evolution remain poorly understood. The structu...
关键词：Three-finger toxins Nicotinic acetylcholine receptor DRIVER 
Why do we study animal toxins?被引量：23
《Zoological Research》2015年第4期183-221,共39页Yun ZHANG 
supported by grants from the National Natural Science Foundation of China(31270835);NSFCYunnan joint funding(U1132601);the Key Research Program of the Chinese Academy of Sciences(KJZD-EW-L03)
Venom （toxins） is an important trait evolved along the evolutionary tree of animals. Our knowledges on venoms, such as their origins and loss, the biological relevance and the coevolutionary patterns with other orga...
关键词：TOXINS Survival competition Evolution Disease mechanism Drug development 
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