LEGIONELLA

作品数：31被引量：39H指数：4
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相关领域：医药卫生更多>>
相关作者：朱庆义詹晓勇胡朝晖李伟英王娜更多>>
相关机构：广州金域医学检验中心同济大学广州金域医学检验中心有限公司中国科学院大学更多>>
相关期刊：《Journal of Life Sciences》《Frontiers of Medicine》《Journal of Water Resource and Protection》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国科学院知识创新工程重要方向项目更多>>
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The DUB blade goes snicker-snack： Novel ubiquitin cleavage by a Legionella effector protein被引量：1
《Cell Research》2017年第7期845-846,共2页Judith A Ronau Mark Hochstrasser 
Recently, a Legionellapneumophila effector protein was shown to have an unprecedented ATP-independent ubiquitin ligase activity that couples phosphoribosylated ubiquitin （PR- Ub） to serine residues of host pro- tein...
A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination被引量：4
《Cell Research》2017年第7期865-881,共17页Jiazhang Qiu Kaiwen Yu Xiaowen Fei Yao Liu Emesto S Nakayasu Paul D Piehowski Jared B Shaw Kedar Puva Chittaranjan Das Xiaoyun Liu Zhao-Qing Luo 
We thank Dr Peter Hollenbeck and Dr Arthur Aronson （Purdue University） for critical reading of the manuscript. We also thank members of the Luo laboratory for helpful discussion. Portions of this work were supported by intemal research fund from the First Hospital of Jilin University; A Team of Science Incentive Grant from PI4D, Purdue University, National Institutes of Health grants R21AI105714 （ZQL）, R01GM103401 （CD） and GM103493 and by National Natural Science Foundation of China grants 21475005 and 21622501 （XL）.
Ubiquitination regulates many aspects of host immunity and thus is a common target for infectious agents. Recent studies have revealed that members of the SidE effector family of the bacterial pathogen Legionella pneu...
关键词：LEGIONELLA bacterial effectors ADP-RIBOSYLATION PHOSPHODIESTERASE 
Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP被引量：4
《Cell Research》2013年第6期775-787,共13页Qin Yu Liyan Hu Qing Yao Yongqun Zhu Na Dong Da-Cheng Wang Feng Shao 
Rab GTPases are emerging targets of diverse bacterial pathogens. Here, we perform biochemical and structural analyses of LepB, a Rab GTPase-activating protein （GAP） effector from Legionellapneumophila. We map LepB G...
关键词：LEGIONELLA Rab GTPases GTPase-activating protein （GAP） type IV secretion system TBC GAP membranetrafficking 
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