WHOLE-CELL

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Cranial irradiation impairs intrinsic excitability and synaptic plasticity of hippocampal CA1 pyramidal neurons with implications for cognitive function被引量：6
《Neural Regeneration Research》2022年第10期2253-2259,共7页Min-Yi Wu Wen-Jun Zou Pei Yu Yuhua Yang Shao-Jian Li Qiang Liu Jiatian Xie Si-Qi Chen Wei-Jye Lin Yamei Tang 
supported by the National Natural Science Foundation of China,Nos.81925031(to YT),81820108026(to YT),81972967(to WJL),81872549(to YL);the Youth Program of National Natural Science Foundation of China,No.81801229(to YTX);a grant from Guangdong Science and Technology Department of China,Nos.2020B1212060018(to WJL),2020B1212030004(to WJL);the Natural Science Foundation of Guangdong Province,No.2019A1515011754(to WJL);the Science and Technology Program of Guangzhou of China,No.202007030001(to YT);the Science and Technology Planning Project of Guangzhou of China,No.201704030033(to YL).
Radiation therapy is a standard treatment for head and neck tumors.However,patients often exhibit cognitive impairments following radiation therapy.Previous studies have revealed that hippocampal dysfunction,specifica...
关键词：GABA-mediated hyperfunction GluR intrinsic excitability long-term potentiation radiation-induced cognitive impairment spontaneous excitatory postsynaptic currents spontaneous inhibitory postsynaptic currents synaptic plasticity type I vesicular glutamate transporter vesicular GABA transporter whole-cell patch clamp recording 
Whole-cell recordings of voltage-gated Calcium,Potassium and Sodium currents in acutely isolated hippocampal pyramidal neurons
《Journal of Nanjing Medical University》2009年第2期122-126,共5页Shuyun Huang Qing Cai Weitian Liu Xiaoling Wang Tao Wang 
supported by Science Development Foundation of Tianjin Institute of Education(20070301)
Objective：To record Calcium, Potassium and Sodium currents in acutely isolated hippocampal pyramidal neurons. Methods：Hippocampal CA3 neurons were freshly isolated by 1 mg protease/3 ml SES and mechanical trituratio...
关键词：patch clamp HIPPOCAMPUS voltage-gated channels WHOLE-CELL 
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