BAICALEIN

作品数:71被引量:386H指数:11
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相关领域:医药卫生更多>>
相关作者:张黎胡燕华王琼李惠勉杨琳更多>>
相关机构:中国药科大学华中科技大学郑州大学第二附属医院北京大学更多>>
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相关基金:国家自然科学基金河南省科技攻关计划国家杰出青年科学基金广东省自然科学基金更多>>
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Baicalein:A potential GLP-1R agonist improves cognitive disorder of diabetes through mitophagy enhancement
《Journal of Pharmaceutical Analysis》2024年第8期1189-1204,共16页Na Liu Xin Cui Wenhui Yan Tingli Guo Zhuanzhuan Wang Xiaotong Wei Yuzhuo Sun Jieyun Liu Cheng Xian Weina Ma Lina Chen 
funded by the Fundamental Research Funds for the Central Universities(Grant No.:xzd012022099);Natural Science Basic Research Program of Shaanxi(Grant Nos.:2023-JC-ZD-47,and 2023-JC-QN-0921);Research Project of Shaanxi Administration of Traditional Chinese Medicine(Project No.:SZY-KJCYC-2023-008);Research Project of Guangxi Administration of Traditional Chinese Medicine(Project No.:GXZYJ20230711);Basic&Clinical Sciences Integration Innovation Project of Xi'an Jiaotong University(Project No.:YXJLRH2022018).
There is increasing evidence that the activation of glucagon-like peptide-1 receptor(GLP-1R)can be used as a therapeutic intervention for cognitive disorders.Here,we have screened GLP-1R targeted compounds from Scutel...
关键词:GLP-1R agonist DIABETES Cognitive disorder MITOPHAGY Cell membrane chromatography 
Effects of urea,metal ions and surfactants on the binding of baicalein with bovine serum albumin被引量:3
《Journal of Pharmaceutical Analysis》2016年第4期256-267,共12页Atanu Singha Roy Amit Kumar Dinda Nitin Kumar Pandey Swagata Dasgupta 
Department of Science and Technology(DST,Project no.SR/SO/BB-54/2007),Government of India for financial support
The interaction of baicalein with bovine serum albumin(BSA) was investigated with the help of spectroscopic and molecular docking studies.The binding affinity of baicalein towards BSA was estimated to be in order of...
关键词:Bovine serum albumin(BSA) Baicalein Binding constant Fluorescence spectroscopy Molecular docking 
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