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Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration被引量：15
《Cell Research》2021年第2期187-205,共19页Chuqian Liang Zunpeng Liu Moshi Song Wei Li Zeming Wu Zehua Wang Qiaoran Wang Si Wang Kaowen Yan Liang Sun Tomoaki Hishida Yanning Cai Juan Carlos lzpisua Belmonte Pedro Guillen Piu Chan Qi Zhou Weiqi Zhang Jing Qu Guang-Hui Liu 
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16010100);the National Key R&D Program of China(2018YFC2000100,2018YFA0107203,2017VFA0102802,2017YFA0103304,2015CB964800,2019YFA0110100);the National Natural Science Foundation of China(81861168034,81921006,81625009,91749202,31671429,91949209,81671377,91749123,81822018,81870228,31801010,81922027,81701388);Program of Beijing Municipal Science and Technology Commission(Z191100001519005);Beijing Natural Science Foundation(Z190019);Beijing Municipal Commission of Health and Family Planning(PXM2018_026283_000002);Advanced Innovation Center for Human Brain Protection(3500-1192012);the Key Research Program of the Chinese Academy of Sciences(KFZD-SW-221);K.C.Wong Education Foundation(GJTD-2019-06,GJTD-2019-08);Youth Innovation Promotion Association of CAS(2016093);the State Key Laboratory of Stem Cell and Reproductive Biology;the State Key Laboratory of Membrane Biology;P.G.was supported by MAPHRE and Fundacion Pedro Guillen.
Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadian clock proteins underlies stem cell aging and whether th...
关键词：DEGENERATION stabilizing CLOCK 
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