supported by the National Natural Science Foundation of China Fund(No 81541060);Science and Technology Projects from the Science Technology and Innovation Committee of Shenzhen Municipality(grant no.JCJY20170818110340383 and JCJY20170307163529489)。
Antisense oligodeoxynucleotide(ASODN)can directly interfere a series of biological events of the target RNA derived from tumor cells through Watson-Crick base pairing,in turn,plays antitumor therapeutic roles.In the s...
Nucleic acid drugs are desirable therapeutics for the treatment of fatal diseases like cancers.For clinical translation of nucleic acid drugs,carrier systems that protect nucleic acid from degradation and help cellula...