This work was supported by the grants from the National Basic Research Program of China(Nos.2015CB943300 and 2017YFC1001403);the National Natural Science Foundation of China(Nos.81630036,91542116,31570920,81490744,31171437,31270969,81571512,and 81501334);the Innovation-oriented Science and Technology Grant from NHC Key Laboratory of Reproduction Regulation(CX2017-2);the Program of Shanghai Academic/Technology Research Leader(17XD1400900);the Shanghai Sailing Program(19YF1404100).
Perturbation of the circadian rhythm damages the biological characteristics of cells and leads to their dysfunction. Rev-erbα, an important gene in the transcription-translation loop of circadian rhythm, is involved ...