Supported by Shanghai Civil Administration Bureau,No.8-2-50.
BACKGROUND Prior studies have noted great variability in the plasma levels of risperidone(RIS).Plasma concentrations of RIS and its active moiety are highly variable and depend on absorption,metabolism,and other predi...
Guangzhou Municipality Medical and Technology Project(Grant No.20131A011087);Beijing Key Lab of Diagnostics and Therapeutics for Psychiatric disorders 2013 Open Foundation(Grant No.2013JSJB01);Beijing Municipal Education Commission Science and Technology Development Program(Grant No.KM201110025025)
Population pharmacokinetic meta-analysis method was used in order to obtain the pharmacokinetic characteristics of risperidone and its active metabolite. Eighteen studies were selected from published papers from 1995 ...
Aim: To study the multiple dose clinical pharmacokinetics of rispeddone and its main active metabolite, 9-hydroxyrisperidone, in Chinese female patients with schizophrenia. Methods: The subjects were 23 Chinese fema...