the National Natural Science Foundation of China(No.81373274) and the State Key Laboratory Cultivatlon Base for the Chemistry and Molecular Engineering of Medicinal Resources, Ministry of Science and Technology of China (No.CHEMR2012-B08).
Based on the asymmetric reduction of alkannin ketone derivative 4 by diisopinocampheylchloro- borane(DIP-C1), a series of shikonin and alkannin derivatives was designed, synthesized and their anticancer activi- ties...
The electrochemical behaviors of shikonin at a poly(diallyldimethylammonium chloride) functionalized graphene sheets modified glass carbon electrode(PDDA-GS/GCE) have been investigated. Shikonin could exhibit a pa...