MESACONITINE

作品数:4被引量:19H指数:3
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相关领域:医药卫生更多>>
相关作者:王晓东许源孙姝琦杜振霞袁小红更多>>
相关机构:北京化工大学西南科技大学成都中医药大学更多>>
相关期刊:《分析测试学报》《Acta Pharmacologica Sinica》《World Journal of Clinical Cases》《Agricultural Science & Technology》更多>>
相关基金:河北省自然科学基金国家自然科学基金国家科技支撑计划更多>>
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Severe aconite poisoning successfully treated with veno-arterial extracorporeal membrane oxygenation:A case report
《World Journal of Clinical Cases》2024年第2期399-404,共6页Saeko Kohara Yoshito Kamijo Ryoko Kyan Ichiro Okada Eiju Hasegawa Soichiro Yamada Koichi Imai Asuka Kaizaki-Mitsumoto Satoshi Numazawa 
BACKGROUND Most species of aconite contain highly toxic aconitines,the oral ingestion of which can be fatal,primarily because they cause ventricular arrhythmias.We describe a case of severe aconite poisoning that was ...
关键词:Aconite poisoning Fatal arrhythmia Veno-arterial extracorporeal membrane oxygenation ACONITINE MESACONITINE Case report 
Inhibition of the INa/K and the activation of peak INa contribute to the arrhythmogenic effects of aconitine and mesaconitine in guinea pigs被引量:9
《Acta Pharmacologica Sinica》2021年第2期218-229,共12页Xiang-chong Wang Qing-zhong Jia Yu-lou Yu Han-dong Wang Hui-cai Guo Xin-di Ma Chun-tong Liu Xue-yan Chen Qing-feng Miao Bing-cai Guan Su-wen Su He-ming Wei Chuan Wang 
supported by the National Natural Science Foundation of China(NSFC,81773828,81770407,81903730);the Natural Science Foundation of Hebei Province(C2011206145,H2018206297,C2018206277,H2019423130);the Research Foundation of Education Bureau of Hebei Province(BJ2019037).
Aconitine(ACO),a main active ingredient of Aconitum,is well-known for its cardiotoxicity.However,the mechanisms of toxic action of ACO remain unclear.In the current study,we investigated the cardiac effects of ACO and...
关键词:ACONITINE MESACONITINE ARRHYTHMIA action potential Na+/K+pump current voltage-gated sodium channel current 
Synthesis and Insecticidal Activity of Derivants of 3,13-Ester Mesaconitine被引量:5
《Agricultural Science & Technology》2009年第3期3-6,共4页王晓东 袁小红 杨海君 侯大斌 王惠 许源 
Supported by Key Projects in the National Science & Technology Pillar Program in the Eleventh Five-year Plan Period(2006BAE01A01-12)~~
[Objective] The experiment aimed to explore the relations between structure of aconitine, aconitine derivatives and insecticide. [Method] The aconitine derivatives such as 3-acetyl mesaconitine, 3-propionyl mesaconiti...
关键词:MESACONITINE DERIVATIVE STRUCTURE Insecticidal activity 
超高效液相色谱串联四极杆质谱联用分析动物血样中乌头类生物碱被引量:5
《分析测试学报》2007年第z1期61-63,共3页杜振霞 孙姝琦 
An ultra performance liquid chromatography-tandem mass spectrum method has been developed for the determination of three aconitum alkaloids (aconitine,hypaconitine and mesaconitine).The three alkaloids were analyzed s...
关键词:ACONITINE HYPACONITINE MESACONITINE Animal blood Ultra performance liquid chromatography-tandem mass spectrum 
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