BACKGROUND Most species of aconite contain highly toxic aconitines,the oral ingestion of which can be fatal,primarily because they cause ventricular arrhythmias.We describe a case of severe aconite poisoning that was ...
supported by the National Natural Science Foundation of China(NSFC,81773828,81770407,81903730);the Natural Science Foundation of Hebei Province(C2011206145,H2018206297,C2018206277,H2019423130);the Research Foundation of Education Bureau of Hebei Province(BJ2019037).
Aconitine(ACO),a main active ingredient of Aconitum,is well-known for its cardiotoxicity.However,the mechanisms of toxic action of ACO remain unclear.In the current study,we investigated the cardiac effects of ACO and...
Supported by Key Projects in the National Science & Technology Pillar Program in the Eleventh Five-year Plan Period(2006BAE01A01-12)~~
[Objective] The experiment aimed to explore the relations between structure of aconitine, aconitine derivatives and insecticide. [Method] The aconitine derivatives such as 3-acetyl mesaconitine, 3-propionyl mesaconiti...
An ultra performance liquid chromatography-tandem mass spectrum method has been developed for the determination of three aconitum alkaloids (aconitine,hypaconitine and mesaconitine).The three alkaloids were analyzed s...