This work was supported by the National Key R&D Program of China(2020YFA0803601);the National Natural Science Foundation of China(32125022 and 32101046);the China Postdoctoral Science Foundation(2019M661348 and 2020T130115).
Brown adipose tissue(BAT)plays a key role in thermogenesis during acute cold exposure.However,it remains unclear how BAT is prepared to rapidly turn on thermogenic genes.Here,we show that damage-specific DNA binding p...