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相关作者:夏婷更多>>
相关机构:约克大学更多>>
相关期刊:《Journal of Computational Mathematics》《Signal Transduction and Targeted Therapy》《Molecular Plant》《Life Metabolism》更多>>
相关基金:国家自然科学基金中国博士后科学基金上海市自然科学基金更多>>
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DDB1 prepares brown adipocytes for cold-induced thermogenesis
《Life Metabolism》2022年第1期39-53,共15页Xu Wang Shen-Ying Liu Guo-Sheng Hu Hao-Yan Wang Guo-Liang Zhang Xiang Cen Si-Ting Xiang Wen Liu Peng Li Haobin Ye Tong-Jin Zhao 
This work was supported by the National Key R&D Program of China(2020YFA0803601);the National Natural Science Foundation of China(32125022 and 32101046);the China Postdoctoral Science Foundation(2019M661348 and 2020T130115).
Brown adipose tissue(BAT)plays a key role in thermogenesis during acute cold exposure.However,it remains unclear how BAT is prepared to rapidly turn on thermogenic genes.Here,we show that damage-specific DNA binding p...
关键词:brown adipose tissue THERMOGENESIS DDB1 RNA polymerase II promoter-proximal pausing UCP1 PGC1α 
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