NEURITOGENESIS

作品数：13被引量：36H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：王晓民更多>>
相关机构：首都医科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Neurology》《Neural Regeneration Research》《Neuroscience Bulletin》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation
《Cell Research》2017年第2期253-273,共21页Shu-Xin Zhang Li-Hui Duan Shun-Ji He Gui-Feng Zhuang Xiang Yu 
We thank Professors Volker Haucke, Marc Kirschner, Alexander Sorisky and Jane Y Wu for constructs. We thank Yuan Lu and Zong-Fang Wan for excellent technical assistance. We thank Dr Qian Hu and ION Optical Imaging Core Facility for confocal microscopy and data analysis support, and Dr Min Jiang and IOBS-Nikon Biological Imaging Center for use of the N-SIM microscope. We are grateful to Drs Xueliang Zhu and Xiumin Yan, colleagues at ION, and members of the Yu laboratory for suggestions and comments. This work was supported by the National Natural Science Foundation of China （31321091 and 31530030）, the Strategic Priority Research Program of the Chinese Academy of Sciences （XDB02010000） and the Science and Technology Commission of Shanghai Municipality （16XD 1404800）.
Neurite initiation is critical for neuronal morphogenesis and early neural circuit development. Recent studies showed that local actin aggregation underneath the cell membrane determined the site of neurite initiation...
关键词：PI（3 4）P2 actin aggregation NEURITOGENESIS SHIP2 PI3K C2α dendritogenesis N-WASP 
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