NEURITOGENESIS

作品数：13被引量：36H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：王晓民更多>>
相关机构：首都医科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Neurology》《Neural Regeneration Research》《Neuroscience Bulletin》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex nanoparticles reverses 6-hydroxydopamine-induced nigrostriatal neurodegeneration被引量：1
《Neural Regeneration Research》2022年第4期854-866,共13页Manuel A.Fernandez-Parrilla David Reyes-Corona Yazmin M.Flores-Martinez Rasajna Nadella Michael J.Bannon Lourdes Escobedo Minerva Maldonado-Berny Jaime Santoyo-Salazar Luis O.Soto-Rojas Claudia Luna-Herrera Jose Ayala-Davila Juan A.Gonzalez-Barrios Gonzalo Flores Maria E.Gutierrez-Castillo Armando JEspadas-Alvarez Irma A.Martínez-Dávila Porfirio Nava Daniel Martinez-Fong 
supported by the Consejo Nacional de Ciencia Tecnología(Conacyt)de México(Grant#254686,to DMF)。
Overexpression of neurotrophic factors in nigral dopamine neurons is a promising approach to reverse neurodegeneration of the nigrostriatal dopamine system,a hallmark in Parkinson's disease.The human cerebral dopamine...
关键词：axonal growth brain-derived neurotrophic factor gene delivery NANOPARTICLES NEURITOGENESIS neuronal cytoskeleton neuroregeneration neurorestoration neurotrophic therapy Parkinson's disease REINNERVATION substantia nigra 
A mimetic peptide of α2,6-sialyllactose promotes neuritogenesis被引量：3
《Neural Regeneration Research》2020年第6期1058-1065,共8页Shuang-Xi Chen Jia-Hui He Yong-Jian Mi Hui-Fan Shen Melitta Schachner Wei-Jiang Zhao 
supported by the National Natural Science Foundation of China,No.81471279 and No.81171138(to WJZ);Talent Support Grant from Shantou University Medical College,China,No.2501220118(to WJZ);the Li Kashing Foundation,No.LD030302(to MS)
Oxidative stress contributes to the pathogenesis of neurodegenerative diseases.With the aim to find reagents that reduce oxidative stress,a phage display library was screened for peptides mimicking a2,6-sialyllactose(...
关键词：central nervous system CEREBELLAR granule neurons MIMETIC peptide neural cell adhesion molecule L1 NEURITOGENESIS NEURODEGENERATIVE disease neuronal survival oxidative stress PHAGE display SAMBUCUS nigra lectin α2 6-sialyllactose 
Author Correction: The natural product 4,10- aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway
《Acta Pharmacologica Sinica》2020年第5期730-730,共5页Sai Chang Wen-chen Ruan Ya-zhou Xu Yun-jie Wang Jie Pang Lu-yong Zhang Hong Liao Tao Pang 
The authors apologize that one image in Fig.2a appeared incorrectly.The representative image for the positive control“NGF”group in Fig.2a is the same as that for the“10μmol/L ARDD in D4”group in Fig.2c.The correc...
关键词：CORRECTION ACTIVATION conclusions 
A growing field: the regulation of axonal regeneration by Wnt signaling被引量：13
《Neural Regeneration Research》2018年第1期43-52,共10页Armando L. Garcia Adanna Udeh Karthik Kalahasty Abigail S. Hackam 
provided by the NEI grant R01EY026546;AU is a recipient of a Research to Prevent Blindness Medical Student Eye Research Fellowship;Financial support from Fight for Sight(summer student fellowship to AU)is gratefully acknowledged;Institutional support is from an NIH Center Core Grant P30EY014801;a Research to Prevent Blindness Unrestricted Grant
The canonical Wnt/β-catenin pathway is a highly conserved signaling cascade that plays critical roles during embryogenesis. Wnt ligands regulate axonal extension, growth cone guidance and synaptogenesis throughout th...
关键词：Wnt signaling NEURITOGENESIS RETINA retinal ganglion cell axonal growth REGENERATION spinal cord 
Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation
《Cell Research》2017年第2期253-273,共21页Shu-Xin Zhang Li-Hui Duan Shun-Ji He Gui-Feng Zhuang Xiang Yu 
We thank Professors Volker Haucke, Marc Kirschner, Alexander Sorisky and Jane Y Wu for constructs. We thank Yuan Lu and Zong-Fang Wan for excellent technical assistance. We thank Dr Qian Hu and ION Optical Imaging Core Facility for confocal microscopy and data analysis support, and Dr Min Jiang and IOBS-Nikon Biological Imaging Center for use of the N-SIM microscope. We are grateful to Drs Xueliang Zhu and Xiumin Yan, colleagues at ION, and members of the Yu laboratory for suggestions and comments. This work was supported by the National Natural Science Foundation of China （31321091 and 31530030）, the Strategic Priority Research Program of the Chinese Academy of Sciences （XDB02010000） and the Science and Technology Commission of Shanghai Municipality （16XD 1404800）.
Neurite initiation is critical for neuronal morphogenesis and early neural circuit development. Recent studies showed that local actin aggregation underneath the cell membrane determined the site of neurite initiation...
关键词：PI（3 4）P2 actin aggregation NEURITOGENESIS SHIP2 PI3K C2α dendritogenesis N-WASP 
The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway被引量：1
《Acta Pharmacologica Sinica》2017年第1期29-40,共12页Sai CHANG Wen-chen RUAN Ya-zhou XU Yun-jie WANG Jie PANG Lu-yong ZHANG Hong LIAO Tao PANG 
Recent studies focus on promoting neurite outgrowth to remodel the central nervous network after brain injury. Currently, however, there are few drugs treating brain diseases in the clinic by enhancing neurite outgrow...
关键词：4 10-aromadendranediol neurite growth PC12 cells NIE115 cells cortical neurons ERK1/2 OGD brain diseases NGF PD98059 XAV939 
Effects of chemical and physical cues in enhancing neuritogenesis and peripheral nerve regeneration
《Neural Regeneration Research》2016年第2期220-221,共2页CaseyD. Sigerson Christopher J. Dipollina Michele Fornaro 
Peripheral nerve injuries are most often a consequence of axonal damage leading to functional losses that may vary from lack of sensitivity distal to the site of injury to complete loss of motor control.The consequenc...
Actin Aggregations Mark the Sites of Neurite Initiation被引量：2
《Neuroscience Bulletin》2016年第1期1-15,共15页Shu-Xin Zhang Li-Hui Duan Hong Qian Xiang Yu 
the ION Optical Imaging Core Facility for technical support;the IOBS-Nikon Biological Imaging Center for use of the N-SIM microscope;supported by grants from the National Natural Science Foundation of China(31125015 and31321091)
A salient feature of neurons is their intrinsic ability to grow and extend neurites, even in the absence of external cues. Compared to the later stages of neuronal development, such as neuronal polarization and dendri...
关键词：Neurite initiation NEURITOGENESIS Actinaggregations - Actin - Microtubules 
Claulansine F promotes neuritogenesis in PC12 cells via the ERK signaling pathway
《Acta Pharmacologica Sinica》2013年第12期1499-1507,共9页Yin-zhong MA Na NING Wen-bin HE Jing-wei LI Jin-feng HU Shi-feng CHU Nai-hong CHEN 
Aim： To study the effects of Claulansine F （Clau F）, a carbazole alkaloid isolated from the stem of Clausena lansium （Lour） Skeels, on neuritogenesis of PC12 cells, and to elucidate the mechanism of action. Meth...
关键词：Claulansine F PC12 cell NEURITOGENESIS GAP-43 ERK1/2 nerve growth factor neurodegenerative disease 
Neuritin: A therapeutic candidate for promoting axonal regeneration被引量：1
《World Journal of Neurology》2013年第4期138-143,共6页Tadayuki Shimada Hiroko Sugiura Kanato Yamagata 
Supported by JSPS KAKENHI partly,No.24700349,No.24659093,No.25293239;MEXT KAKENHI,No.25110737
Following injury, the axons of the mammalian central nervous system do not regenerate. Many studies have aimed at understanding the mechanisms that prevent axonal regeneration and at designing ways to overcome the obs...
关键词：AXONAL regeneration NEURONAL development AXONAL injury NEURITOGENESIS EPILEPSY 
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