supported in part by the National Natural Science Foundation of China,Nos.81927804(to GL),82260456(to LY),U21A20479(to LY);Science and Technology Planning Project of Shenzhen,No.JCYJ20230807140559047(to LY);Key-Area Research and Development Program of Guangdong Province,No.2020B0909020004(to GL);Guangdong Basic and Applied Research Foundation,No.2023A1515011478(to LY);the Science and Technology Program of Guangdong Province,No.2022A0505090007(to GL);Ministry of Science and Technology,Shenzhen,No.QN2022032013L(to LY)。
Neural machine interface technology is a pioneering approach that aims to address the complex challenges of neurological dysfunctions and disabilities resulting from conditions such as congenital disorders,traumatic i...
supported by PLA General Hospital Program,No.LB20201A010024(to LW).
Neurotrophic keratopathy is a persistent defect of the corneal epithelium,with or without stromal ulceration,due to corneal nerve deficiency caused by a variety of etiologies.The treatment options for neurotrophic ker...
supported in part by the National Natural Science Foundation of China,Nos.U1913601,81927804;the Key-Area Research and Development Program of Guangdong Province,No.2020B0909020004(GL);the National Natural Science Foundation of China,Nos.81960419,82260456(both to LY)。
Targeted muscle reinnervation has been proposed for reconstruction of neuromuscular function in amputees.However,it is unknown whether performing delayed targeted muscle reinnervation after nerve injury will affect re...
Dear Editor,Chronic pain is a significant concern after major lower limb amputations that often preclude prosthetic fitting,decrease ambulation,and impact the quality of life[1,2].In the last decade,targeted muscle re...
Aim:Targeted muscle reinnervation(TMR)surgery has fundamentally changed the management of patients who have suffered or are about to undergo amputation.Providing nerve stumps with a muscle target has been shown to hav...
Targeted muscle reinnervation(TMR)is a peripheral nerve procedure that can prevent and treat postamputation pain.The nerve transfer allows for organized nerve regeneration and repair after amputation surgery.The proce...
funded by the National Natural Science Foundation of China,Nos.81760416,81960419,81927804(all to LY);Science and Technology foundation of Guizhou Province,No.[2017]1226(to LY);Support Plan for High Level Talents in Guizhou High Education Institutions,No.KY[2018]056(to LY).
Targeted muscle reinnervation(TMR)is a surgical procedure used to transfer residual peripheral nerves from amputated limbs to targeted muscles,which allows the target muscles to become sources of motor control informa...
supported by the Li Kashing Foundation(to MS);the FoRUM grant F957N-2019 of the Ruhr-University Bochum(to DL);the Heinrich und Alma Vogelsang Stiftung(to IJ).
The role that the immune system plays after injury of the peripheral nervous system is still not completely understood.Perforin,a natural killer cell-and T-lymphocyte-derived enzyme that mediates cytotoxicity,plays im...
the National Natural Science Foundation of China,No.81171147(to LXL);“Key Medical Talents of Qiangwei Project”Research Foundation of Health Department of Jiangsu Province,No.ZDRCA2016010(to LXL);“Xingwei Project”Key Personal Medical Research Foundation of Health Department of Jiangsu Province,No.RC201156(to LXL);Jiangsu Province’s Key Discipline of Medicine,No.XK201117(to LXL);the Priority Academic Program Development of Jiangsu Higher Education Institutions,PAPD(to LXL);the Natural Science Foundation of Jiangsu Province,No.BK20171064(to BSH).
There is no effective treatment for hemiplegia after hypertensive intracerebral hemorrhage.Considering that the branches of L4 nerve roots in the lumbar plexus root control the movement of the lower extremity anterior...
supported by the Consejo Nacional de Ciencia Tecnología(Conacyt)de México(Grant#254686,to DMF)。
Overexpression of neurotrophic factors in nigral dopamine neurons is a promising approach to reverse neurodegeneration of the nigrostriatal dopamine system,a hallmark in Parkinson's disease.The human cerebral dopamine...