PERFORIN

作品数：32被引量：81H指数：6
导出分析报告
相关领域：医药卫生更多>>
相关作者：王一理李儒佑韩晓伟马贤德关洪全更多>>
相关机构：吉林大学西安交通大学武汉大学徐州医科大学更多>>
相关期刊：《World Journal of Emergency Medicine》《Neural Regeneration Research》《World Journal of Clinical Cases》《中国免疫学杂志》更多>>
相关基金：国家自然科学基金国家科技攻关计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
活动性结核病患者自然杀伤(NK)细胞CD160的表达及其与细胞功能的关系被引量：1
《细胞与分子免疫学杂志》2022年第10期918-924,共7页杨秉芬 翟斐 安红娟 曹志红 刘艳华 王若 程小星 
重大专项课题(2017ZX10201301-007-002);解放军总医院第八医学中心重点课题(2017ZD-007)。
目的分析外周血单个核细胞(PBMC)中CD160 mRNA和蛋白的表达与结核病免疫的关系。方法使用荧光定量PCR检测PBMC中CD160 mRNA的表达,流式细胞术分析PBMC中主要细胞群(T细胞、B细胞、自然杀伤(NK)细胞和单核细胞)表面CD160蛋白表达情况,使...
关键词：肺结核 NK细胞 CD160 γ干扰素(IFN-γ) 穿孔素(perforin) 颗粒酶B(granzyme B) 颗粒溶素(granulysin) CD69 CD107 
Caspase-7 and acid sphingomyelinase:partner repairmans of gasdermin and perforin pores
《Signal Transduction and Targeted Therapy》2022年第9期3172-3173,共2页Ke Jin Guofang Shen 
This work was supported by the Chinese National Natural Science Funds(81902947).
Recently,a work published in Nature by Kengo Nozaki et al.revealed a novel mechanism for plasma membrane pores'repair mediated by caspase-7.In this work,they found caspase-7 facilitated Intestinal epithelial cell(IEC)...
关键词：MYELIN al. pores 
Mice lacking perforin have improved regeneration of the injured femoral nerve
《Neural Regeneration Research》2022年第8期1802-1808,共7页Igor Jakovčevski Monika von Düring David Lutz Maja Vulović Mohammad Hamad Gebhard Reiss Eckart Förster Melitta Schachner 
supported by the Li Kashing Foundation(to MS);the FoRUM grant F957N-2019 of the Ruhr-University Bochum(to DL);the Heinrich und Alma Vogelsang Stiftung(to IJ).
The role that the immune system plays after injury of the peripheral nervous system is still not completely understood.Perforin,a natural killer cell-and T-lymphocyte-derived enzyme that mediates cytotoxicity,plays im...
关键词：blood-nerve barrier femoral nerve injury locomotor recovery LYMPHOCYTES MYELINATION NK-cells PERFORIN REINNERVATION 
Adult onset type 2 familial hemophagocytic lymphohistiocytosis with PRF1 c.65delC/c.163C>T compound heterozygous mutations: A case report被引量：2
《World Journal of Clinical Cases》2021年第10期2289-2295,共7页Xin-Yi Liu Yan-Bo Nie Xue-Jing Chen Xiao-Hui Gao Li-Jia Zhai Feng-Ling Min 
the Project of Key Talents of Strengthening Health through Science and Education of Yangzhou City,China,No.ZDRC201813.
BACKGROUND Familial hemophagocytic lymphohistiocytosis(FHL)is a primary immunodeficiency disease caused by gene defects.The onset of FHL in adolescents and adults may lead clinicians to ignore or even misdiagnose the ...
关键词：Familial hemophagocytic lymphohistiocytosis PERFORIN PRF1 mutation Lateonset Case report 
Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy被引量：8
《Cellular & Molecular Immunology》2019年第6期611-620,共10页Yuying Liu Tianzhen Zhang Yabo Zhou Jiping Li Xiaoyu Liang Nannan Zhou Jiadi Lv Jing Xie Feiran Cheng Yiliang Fang Yunfeng Gao Ning Wang Bo Huang 
supported by grants from Chinese Academy of Medical Sciences(CAMS)Initiative for Innovative Medicine(CAMS-I2M)2017-I2M-1-001,the National Natural Science Foundation of China(81788101,81661128007,81530080,and 81773062);the CAMS Initiative for Innovative Medicine(2016-I2M-1–007).
Different types of pores ubiquitously form in cell membranes,leading to various types of cell death that profoundly influence the fate of inflammation and the disease status.However,these pores have never truly been v...
关键词：membrane pore formation AFM PERFORIN GSDMD/GSDME COMPLEMENT 
Expressions and significances of IFN-γ, IL-10, TGF-β, PFP and GNLY in serum of children with Henoch Schonlein purpura
《Journal of Hainan Medical University》2018年第23期34-37,共4页Tao-Min Bai 
Objective:To investigate the expressions of interferon-γ (IFN-γ), interleukin-10 (IL-10), transforming growth factor-β (TGF-β), perforin (PFP) and granulysin (GNLY) in serum of children with Henoch-Schonlein purpu...
关键词：Henoch-Schonlein PURPURA INTERFERON-Γ Interleukin 10 Transforming growth factor-β PERFORIN GRANULYSIN 
Microwave-induced Apoptosis and Cytotoxicity of NK Cells through ERK1/2 Signaling被引量：6
《Biomedical and Environmental Sciences》2017年第5期323-332,共10页ZHAO Li LI Jing HAO Yan Hui GAO Ya Bing WANG Shui Ming ZHANG Jing DONG Ji ZHOU Hong Mei LIU Shu Chen PENG Rui Yun 
supported by National Science Foundation of China(No.81172620)
Objective To investigate microwave-induced morphological and functional injury of natural killer（NK） cells and uncover their mechanisms. Methods NK-92 cells were exposed to 10, 30, and 50 m W/cm^2 microwaves for 5 m...
关键词：Microwave Natural killer cells Cytotoxicity Apoptosis Cell cycle Perforin 
Cholangiocarcinoma-derived exosomes inhibit the antitumor activity of cytokine-induced killer cells by down-regulating the secretion of tumor necrosis factor-α and perforin被引量：6
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2016年第7期537-544,共8页Jiong-huang CHEN Jian-yang XIANG Guo-ping DING Li-ping CAO 
Project supported by the National Natural Science Foundation of China(No.81272671);the Foundation of Health and Family Planning Commission of Zhejiang Province(No.2015KYB218);China
Objective： The aim of our study is to observe the impact of cholangiocarcinoma-derived exosomes on the antitumor activities of cytokine-induced killer （CIK） cells and then demonstrate the appropriate mechanism. Met...
关键词：CHOLANGIOCARCINOMA Tumor-derived exosomes Cytokine-induced killer cells Immune escape 
白色念珠菌肠道感染对脾虚小鼠小肠组织中Perforin和Granzyme的影响被引量：3
《中国中医基础医学杂志》2015年第12期1519-1521,共3页马贤德 韩晓伟 关洪全 
国家自然科学基金资助项目(81173145);辽宁中医药大学省部共建中医脏象理论及应用教育部重点实验室
目的:通过对脾虚感染白色念珠菌小鼠小肠超微结构及黏膜组织中Perforin、Granzyme表达水平的观察,探讨机体在脾虚状态下感染白色念珠菌的部分免疫机制。方法:健康SPF级昆明种小白鼠60只,按随机数字表法分为空白对照组(N1组15只)、空白...
关键词：脾虚证 白色念珠菌 感染 穿孔素 颗粒酶 
Role for urinary biomarkers in diagnosis of acute rejection in the transplanted kidney被引量：4
《World Journal of Transplantation》2015年第4期251-260,共10页Basma Merhi George Bayliss Reginald Y Gohh 
Despite the introduction of potent immunosuppressive medications within recent decades, acute rejection still accounts for up to 12% of all graft losses, and is generally associated with an increased risk of late graf...
关键词：URINARY biomarkers Acute renal allograft rejection Serum creatinine Graft outcome URINARY perforin granzyme B and FAS-LIGAND MRNA URINARY CXCL9 and CXCL10 URINARY FOXP3 MRNA URINARY miRNA 
全选清除导出
共4页<1234>
检索报告 对象比较 聚类工具 使用帮助 返回顶部