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作品数:10被引量:50H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Asian Journal of Andrology》《Cell Research》《Cancer Drug Resistance》更多>>
相关基金:国家自然科学基金更多>>
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  • 期刊=Cell Researchx
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LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer
《Cell Research》2025年第1期59-71,共13页Fei Li Pengfei Dai Huili Shi Yajuan Zhang Juan He Anuradha Gopalan Dan Li Yu Chen Yarui Du Guoliang Xu Weiwei Yang Chao Liang Dong Gao 
supported by the National Science Fund for Distinguished Young Scholars(32125013);the Excellent Young Scholars Fund(82422052);the National Natural Science Foundation of China(92253304,82002718,92357301,92253305,82461160322);the National Key R&D Program of China(2023YFC2506401);the Jiangsu Natural Science Foundation(BK20191077);the China National Postdoctoral Program for Innovative Talents(BX2021306,BX2024370);the Shanghai Oriental Talent Program,Shanghai Science and Technology Development Funds(22QA1409900,23ZR1470100);Shanghai Municipal Science and Technology Major Project,the Sanofi Scholarship and Heaye Program.
Epigenetic regulation profoundly influences the fate of cancer cells and their capacity to switch between lineages by modulating essential gene expression,thereby shaping tumor heterogeneity and therapy response.In ca...
关键词:LKB1 INACTIVATION PLASTICITY 
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